Tag: OCRA Research

OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations

A long-running study from Dana-Farber Cancer Institute, published in Nature Cancer and co-funded by OCRA, has discovered that the antibiotic novobiocin is capable of targeting and killing tumor cells in laboratory cell lines and tumor models with…

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OCRA-Funded Research Provides a New Understanding of Ovarian Cancer Biology

OCRA-funded researcher Anil K. Sood, M.D., lead and senior author, and Sanghoon Lee, Ph.D…

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OCRA-Funded Scientists Further Study Gene Mutation Connected to Ovarian Cancer

An international collaborative of scientists, including Dr. Ronald Chandler at Michigan State University, studied ARID1A mutations, which are specific gene mutations observed in deep ovarian and deep infiltrating endometriosis…

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OCRA-Funded Study Finds Menopausal Hormone Therapy Associated with Improved Survival from Ovarian Cancer

(July 27, 2020) Research from the Ovarian Cancer Association Consortium (OCAC) found that “using menopausal hormone therapy prior to diagnosis extends ovarian cancer survival…

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OCRA Awards $6.6 Million in Ovarian Cancer Research Grants for 2020

(January 13, 2020) Thanks to your support, 22 top scientists at 19 eminent medical centers across the world will delve into important topics across the ovarian cancer landscape…

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OCRA-Funded Research Advances Immunotherapy

(December 23, 2019) OCRA-funded scientist Dr. Sarah Gitto is making strides toward better harnessing the immune system to fight ovarian cancer. As reported recently in Gynecologic Oncology, Dr…

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OCRA-Funded Research Breakthroughs in 2019

OCRA-funded scientists have been hard at work this year, uncovering breakthroughs in ovarian cancer prevention, diagnostics, and treatment that can save women’s lives…

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OCRA-Funded Research Yields Insight into Clear Cell Ovarian Cancers

(November 13, 2019) A study recently published in Nature Communications and led by OCRA grantee Dr. Rugang Zhang showed that the ARID1A protein plays a fundamental role in ensuring correct chromosome segregation when the cells divide…

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OCRA-Funded Research Explores New Pathways for Understanding Metastases

(October 30) In an effort to further understand disease initiation and progression, OCRA grantee Dr…

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OCRA-Funded Research Elucidates New Immunotherapy Approach

(September 19, 2019) While harnessing the immune system has resulted in strong responses for a subset of cancer patients, the majority of patients have remained unresponsive to this approach…

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OCRA-Funded Research Points to Surrounding Tissues for Further Study

(September 10, 2019) Ovarian clear-cell carcinoma is an aggressive form of ovarian cancer.  Endometriosis is derived from the uterine endometrium and is a known risk factor for ovarian clear-cell carcinoma…

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OCRA-Funded Research Moves Immunotherapy Forward

(September 5, 2019) OCRA funded investigator Dmitriy Zamarin, MD, PhD contributed to a study that provides an intriguing hypothesis that mutation in genes like SMARCA4 may improve tumor recognition by the immune system…

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