Tag: OCRA Research

OCRFA Funded Research Identifies Mechanism Underlying Ovarian Cancer Development

(November 22, 2017) A recent paper published in the Journal of Clinical Investigation reports that a subset of ovarian cancers reduce the expression of a critical gene involved in recycling the cells’ proteins, known as ubiquitin B (UBB)…

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OCRFA Funded Study Discovers 3 Key Genes in Prevention and Treatment of BRCA1 and BRCA2 Tumors

(October 19, 2017) BRCA1 and BRCA2 are among the most frequently mutated genes in ovarian cancer…

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OCRFA Funded Study Determines the Importance of Tumor Antigen

(May 2, 2017) A study, published in Gynecologic Oncology, revealed the importance of tumor antigen NY-ESO-1 for ovarian cancer patients…

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OCRFA Funded Study Looks at the Link Between Hypertension and Ovarian Cancer

(April 25, 2017) Researchers from Roswell Park Cancer Institute used data from 15 different studies that were part of the Ovarian Cancer Association Consortium, partially funded by OCRFA, to examine the relationship between epithelial ovarian cancer…

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OCRFA Research Finds New Genetic Variants Linked to Ovarian Cancer

A study published in Nature Genetics has identified nine new susceptibility loci, or disease-associated alleles, for different epithelial ovarian cancer (EOC) histotypes and three susceptibility loci within BRCA1 and 2 mutation carriers with EOC…

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OCRFA Research Finds New Gene Mutation Spurs Cancer Growth

(February 7, 2017) An OCRFA funded study, published on January 13, 2017 in Oncotarget, sheds light on EMSY, a gene that researchers at New York University Langone Medical Center now understand to have a role similar to those of BRCA1 and BRCA2…

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OCRFA Funded Research Studies DNA Repair in Ovarian Cancer Cells

(January 30, 2017) In a study funded in part by OCRFA, and published this month in Oncotarget, researchers, including first author and former OCRFA grantee Petar Jelinic, PhD, studied EMSY, a putative BRCAness gene, and its role in the suppression…

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OCRFA Awards $5.6 Million in Scientific Research Grants for 2017

(January 20, 2017) OCRFA has awarded $5.6 million in new scientific research grants for ovarian cancer, bringing our total investment in life-saving research to over $75 million…

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Five Important Discoveries from OCRFA-Funded Researchers in 2016

OCRFA-funded scientists are working hard to save women’s lives…

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OCRFA Funded Research Identifies Protein Group Responsible For Senescence’s Negative Side Effects

(Nov. 3, 2016) Senescence is the state when normal, healthy cells no longer have the ability to divide, which can occur during chemotherapy or when cancer genes within that cell are activated…

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OCRFA Funded Study Explores New Role of Estrogen in Anti-Tumor Immunity

(October 31, 2016) Estrogen signaling is a known factor in how certain estrogen receptive (ER positive) tumors grow in breast and ovarian cancers…

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OCRFA Research Shows Drugs Help Anti-Tumor Immunity

(October 5, 2016) A team of researchers, including senior author and former OCRFA grantee Rugang Zhang, PhD, have been studying the relationship between PD-1 and PD-L1, a protein and an accompanying molecule, and t-cells, which are a body’s…

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