Chin-Chi Chen, PhD

Chin-Chi Chen, PhD

Dr. Chin-Chi Chen is currently a postdoctoral researcher at the Johns Hopkins University School of Medicine in Baltimore, Maryland. Dr. Chen earned her Ph.D. in Genetics and Genomics from the University of Connecticut in 2016. She conducted her doctoral research under the mentorship of Dr. Barbara Mellone, where she focused on understanding the regulatory mechanisms of centromeric chromatin during events of cell division. As a graduate student, she was awarded the Claire M. Berg Graduate Fellowship in recognition of her research achievements. Her graduate work has resulted in several first-author publications, one of which has been highlighted in the Journal of Cell Biology. After her Ph.D., she joined a gynecologic pathology laboratory under the instructions of Dr. Ie-Ming Shih and Dr. Tian-Li Wang. Dr. Chen’s project investigates the molecular regulation of ARID1A related to the repair of DNA damage, and the pathogenic role of ARID1A mutation in ovarian cancer development. Since ARID1A mutations are highly prevalent in gynecologic cancer, her ongoing work provides a biological rationale and mechanistic insight into the development of ARID1A-based precision cancer medicine.