Diana Hargreaves, PhD

Diana Hargreaves, Ph.D. is currently a postdoctoral scholar in the laboratory of Gerald Crabtree at Stanford University. She is investigating the function of a protein, ARID1A, which has recently been shown to be frequently mutated in clear-cell and endometrioid ovarian cancer. ARID1A is a member of a complex of proteins, the BAF complex, which utilizes energy derived from ATP to alter DNA structure. Using a combination of biochemistry and mouse genetics, she hopes to uncover how ARID1A functions within this complex to protect cells from becoming oncogenic. Diana received her Ph.D. from the Department of Immunology at Yale University under the guidance of Dr. Ruslan Medzhitov and her B.S. from Haverford College. Diana was awarded the NSF Graduate Research Fellowship as a graduate student and is currently sponsored by a fellowship from the Helen Hay Whitney Foundation.