Ie-Ming Shih, MD, PhD

Ie-Ming Shih, MD, PhD

Richard TeLinde Distinguished Professor of Gynecologic Pathology
Co-Director, Breast and Ovarian Cancer Program
Johns Hopkins University School of Medicine

Dr. Ie-Ming Shih is the Richard TeLinde Distinguished Professor (Endowed Chair) of Gynecologic Pathology and directs this research program at the Johns Hopkins University School of Medicine (1,2). He also co-directs the Breast and Ovarian Cancer Program (3) at the Sidney Kimmel Comprehensive Cancer Center at Hopkins. Dr. Shih received his MD from Taipei Medical University and PhD from the University of Pennsylvania. He is a board-certified pathologist, having completed a clinical fellowship in gynecologic pathology followed by a cancer molecular genetics fellowship at Hopkins. His research focuses on exploring the genomics and pathogenesis of ovarian and endometrial cancer, developing new target-based therapy and applying innovative technology for early detection of gynecologic cancer (2). Dr. Shih’s research laboratory has made several discoveries that contribute to our understanding of the pathogenesis of ovarian cancer, including uncovering the genomic landscapes of different histologic subtypes of ovarian cancer, new mechanisms behind chemoresistance, the tumor suppressor roles of ARID1A, and the possible origin of ovarian high-grade serous carcinoma.

Several researchers in the TeLinde Gynecologic Pathology Research Program and Cancer Center have been devoted to identifying and characterizing potential new molecules that can be exploited to target ovarian cancer. The timely and generous gift from the OCRA allows him to build a research team devoted to developing new treatment modalities to improve clinical outcome in ovarian cancer patients. Dr. Shih has published extensively in the field of ovarian cancer research and served on many advisory and editorial boards. In addition to his clinical, research, and teaching obligations, Dr. Shih is also a passionate photographer (4) who wishes to use his talent to help raise fund for ovarian cancer research.