Joshua Doloff, PhD

Joshua C. Doloff is an Assistant Professor in Biomedical Engineering, Materials Science, and Oncology (Cancer Immunology) at Johns Hopkins University. At the Translational Tissue Engineering Center, Sidney-Kimmel Comprehensive Cancer Center (SKCCC), and Bloomberg-Kimmel Institute (BKI) for Cancer Immunotherapy, his lab focuses on Immunoengineering and Regenerative Medicine, with emphasis on cancer, implant/transplant rejection responses, and autoimmunity. Josh earned his undergraduate Bioengineering degree at the University of Pennsylvania, where he carried out biomaterials and tissue engineering research in the Ducheyne Lab. Later, to better understand what happens when deliverables are introduced into the body, Joshua focused his PhD in the Waxman Lab at Boston University on host immune responses to varied therapeutics. Early work on cancer-targeted viral vectors won technology development and University Provost awards. Later work produced insights into chemotherapy-induced anti-tumor immunity. Highlighting his achievements, Joshua was awarded the Frank A. Belamarich Award for Best Doctoral Research in his graduating class. Josh went on to become a Juvenile Diabetes Research Foundation (JDRF) Postdoctoral Fellow in the Langer and Anderson labs at the Koch Institute at MIT. There, his work on deciphering immune-mediated biomaterial and biomedical device implant rejection contributed to numerous top publications, patents, a lab startup—Sigilon, and awards—including top presentation selections, Immunoengineering prizes, co-chair honors, and a Rising Star Alumni Award. Most recently, Josh was elected the new Chair of SFB’s Immunoengineering SIG (after his tenure as Vice-Chair), and has received multiple awards, including a Controlled Release Society Young Investigator Award for Immuno Delivery, a Cellular and Molecular Bioengineering Young Innovator (2021), NIH Trailblazer, additional support through the JDRF, FDA, Maryland Stem Cell Research Foundation (MSCRF), and DARPA, and most recently an Early Career Investigator Award from the Ovarian Cancer Research Alliance.