Nicole Gull, PhD

Dr. Nicole Gull is currently a bioinformatics postdoctoral scientist at Cedars Sinai Medical Center under the mentorship of Dr. Michelle Jones. Her current work focuses on identifying somatic alterations in recurrent ovarian cancer. She received her bachelor’s degree in Biological Sciences and Psychology from Carnegie Mellon University. Before pursuing her doctorate, her enthusiasm for research and cancer biology was fostered in the lab of Dr. Antonio DiCristofano at Fox Chase Cancer Center in Philadelphia, PA. The lab’s research focused on thyroid proliferative disorders, specifically dysfunction of PTEN and the PI3K/AKT/mTOR pathway. During her PhD, she worked under the supervision of Dr. Benjamin Berman where her projects focused on identifying DNA methylation alterations which result in changes to gene expression and DNA stability. Her studies allowed her to develop a novel bioinformatics pipeline and utilize advanced statistical methods, machine learning, and bioinformatics tools to better understand the epigenetic changes underlying chemoresistance in ovarian cancer patients. This funding will expand her current project to determine the effect of homologous recombination on immune cell infiltration and inflammasome activation within recurrent ovarian cancer, using proteomics and spatial phenotyping.