Sumegha Mitra, PhD

Dr. Sumegha Mitra is an Assistant Professor in the Department of Obstetrics and Gynecology at Indiana University Purdue University Indianapolis (IUPUI). Dr. Mitra completed her Ph.D. from University of Mumbai, India and was an Indian Council of Medical Research fellow. She joined the University of Chicago for her postdoctoral studies in Dr. Joe G. N. Garcia’s laboratory. She studied the mechanistic role of K63-specific ubiquitination in the activation of Akt signaling under mechanical stress. Subsequently, she completed her postdoctoral studies in Garcia lab at the University at Illinois (UIC) at Chicago. She was awarded with UIC Campus Research Board pilot grant. Currently, she studies the role ubiquitin signaling in ovarian cancer progression. Several components of ubiquitin proteasome system play a key role in mediating cancer signaling and are implicated as oncogenes or tumor suppressors. She also investigates the functional role of small-molecule inhibitors from ubiquitin proteasome system as adjuvant therapy for ovarian cancer. Her research is supported by Biomedical Research Grant from Indiana University School of Medicine and Ralph W. and Grace M. Showalter Research Trust.