Research News

OCRA-Funded Research Reveals New Ovarian Cancer Biomarker and Growth Mechanisms

Researchers at UT Southwestern have discovered a potential “Achilles’ heel” in ovarian cancer cells, and a new biomarker that may open up more avenues for targeted therapies. The study, published in the journal Cell, was led by W…

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Oral Contraceptives Associated with Lower Ovarian Cancer Risk in BRCA Mutation Carriers

A study published in the American Journal of Obstetrics & Gynecology provides new insight into previously established research that oral contraceptive use is connected to lower ovarian cancer risk in the general population, by more closely…

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OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations

A long-running study from Dana-Farber Cancer Institute, published in Nature Cancer and co-funded by OCRA, has discovered that the antibiotic novobiocin is capable of targeting and killing tumor cells in laboratory cell lines and tumor models with…

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Seeking New Insights Into Origins of Ovarian Cancer | Meet a Scientist

“It’s kind of like how the Apollo mission to the moon gave us Velcro.” Dr…

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OCRA-Funded Research Uncovers New Checkpoint Mechanism, Potential New Therapeutic Target

New research from The Wistar Institute and Peter MacCallum Cancer Center has uncovered a previously unknown checkpoint mechanism for gene expression, that may open up new avenues for transcription-based targeted cancer therapies in the future…

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Large Study Suggests Ovarian Cancer Screening in General Public Doesn’t Save Lives

Results from a large British clinical trial, which involved more than 200,000 post-menopausal women who were followed for more than 15 years, showed that screening average-risk, asymptomatic women for ovarian cancer does not reduce deaths from the…

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Highlights: 2021 Virtual Annual Meeting of the American Association for Cancer Research (AACR)

The first part of this year’s annual meeting of the AACR was titled “Discovery Science Driving Clinical Breakthroughs” and was held virtually from April 10 to 14, 2021…

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Highlights: 2021 Virtual Annual Meeting of the Society of Gynecologic Oncology (SGO)

2021 SGO Virtual Meeting Themes This year’s Society of Gynecologic Oncology annual meeting was held virtually, with most sessions held March 19 to 21, 2021…

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The Overview: April 2021

Flowers are blooming all around us, people are beginning to rediscover the things that matter most, and every day, OCRA grantees are making strides in understanding even more about ovarian cancer…

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Rare Ovarian Cancers: Research Updates

Every year, more than 22,000 people are diagnosed with ovarian cancer. Most (85% – 90%) will be diagnosed with a form of epithelial ovarian cancer; and among these, most will be high-grade serous ovarian cancer (HGSOC)…

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New Study Highlights Importance of Mental Health Support for Ovarian Cancer Patients

Researchers at the University of Utah and Huntsman Cancer Institute found that an ovarian cancer diagnosis took a much higher mental toll on patients and survivors than initially expected at the start of the study, thus underscoring the…

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Vulnerability in ARID1A-Mutant Cancer Cells Could Provide New Pathways for OCCC Treatment

OCRA grantees Dr. Rugang Zhang and Dr. Shuai Wu, both of The Wistar Institute, along with colleagues, have discovered a vulnerability in cancer cells that harbor certain genetic mutations…

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