Research News
Study Finds Germline Ovarian Cancer Mutations Occur Equally in Black and White Patients
A recent study has shed more light on the demographics of hereditary ovarian cancer, and provides further data to suggest an urgent need for increased genetic counseling for potentially high-risk Black women, as well as increased genetic testing in…
Finding the Story in the Data | Meet a Scientist
Sridevi Challa, PhD, an OCRA grantee at UT Southwestern, is on the receiving end of some major accolades…
OCRA-Funded Study Identifies Role of Enzyme in Ovarian Cancer Progression
OCRA grantee Dr. Sumegha Mitra of Indiana State University and colleagues have identified the mechanism by which a specific enzyme known as UCHL1 promotes the growth of high-grade serous ovarian cancer in some patients…
Groundbreaking Initiative Seeks to Accelerate Development of New Treatments with OCRA’s Support
LOS ANGELES – (BUSINESS WIRE)–Global Coalition for Adaptive Research (GCAR) announces a new clinical trial initiative, Ovarian CanceRxTM…
OCRA-Funded Research Reveals New Ovarian Cancer Biomarker and Growth Mechanisms
Researchers at UT Southwestern have discovered a potential “Achilles’ heel” in ovarian cancer cells, and a new biomarker that may open up more avenues for targeted therapies. The study, published in the journal Cell, was led by W…
Oral Contraceptives Associated with Lower Ovarian Cancer Risk in BRCA Mutation Carriers
A study published in the American Journal of Obstetrics & Gynecology provides new insight into previously established research that oral contraceptive use is connected to lower ovarian cancer risk in the general population, by more closely…
OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations
A long-running study from Dana-Farber Cancer Institute, published in Nature Cancer and co-funded by OCRA, has discovered that the antibiotic novobiocin is capable of targeting and killing tumor cells in laboratory cell lines and tumor models with…
Seeking New Insights Into Origins of Ovarian Cancer | Meet a Scientist
“It’s kind of like how the Apollo mission to the moon gave us Velcro.” Dr…
OCRA-Funded Research Uncovers New Checkpoint Mechanism, Potential New Therapeutic Target
New research from The Wistar Institute and Peter MacCallum Cancer Center has uncovered a previously unknown checkpoint mechanism for gene expression, that may open up new avenues for transcription-based targeted cancer therapies in the future…
Large Study Suggests Ovarian Cancer Screening in General Public Doesn’t Save Lives
Results from a large British clinical trial, which involved more than 200,000 post-menopausal women who were followed for more than 15 years, showed that screening average-risk, asymptomatic women for ovarian cancer does not reduce deaths from the…
Highlights: 2021 Virtual Annual Meeting of the American Association for Cancer Research (AACR)
The first part of this year’s annual meeting of the AACR was titled “Discovery Science Driving Clinical Breakthroughs” and was held virtually from April 10 to 14, 2021…
Highlights: 2021 Virtual Annual Meeting of the Society of Gynecologic Oncology (SGO)
2021 SGO Virtual Meeting Themes This year’s Society of Gynecologic Oncology annual meeting was held virtually, with most sessions held March 19 to 21, 2021…