Research News

OCRA-Funded Study Points to New Approach to Improve Ovarian Cancer Treatment

The following is a press release from University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, and Magee-Womens Research Institute PITTSBURGH, Nov…

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The Overview: October 2021

Have we got a roundup in store! You heard from us a lot in September (thanks to you, we surpassed our Ovarian Cancer Awareness Month fundraising goal!) and there’s still so much to report … research progress, a brand new clinical trial…

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Study Finds Germline Ovarian Cancer Mutations Occur Equally in Black and White Patients

A recent study has shed more light on the demographics of hereditary ovarian cancer, and provides further data to suggest an urgent need for increased genetic counseling for potentially high-risk Black women, as well as increased genetic testing in…

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Finding the Story in the Data | Meet a Scientist

Sridevi Challa, PhD, an OCRA grantee at UT Southwestern, is on the receiving end of some major accolades…

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OCRA-Funded Study Identifies Role of Enzyme in Ovarian Cancer Progression

OCRA grantee Dr. Sumegha Mitra of Indiana University and colleagues have identified the mechanism by which a specific enzyme known as UCHL1 promotes the growth of high-grade serous ovarian cancer in some patients…

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Groundbreaking Initiative Seeks to Accelerate Development of New Treatments with OCRA’s Support

LOS ANGELES – (BUSINESS WIRE)–Global Coalition for Adaptive Research (GCAR) announces a new clinical trial initiative, Ovarian CanceRxTM…

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OCRA-Funded Research Reveals New Ovarian Cancer Biomarker and Growth Mechanisms

Researchers at UT Southwestern have discovered a potential “Achilles’ heel” in ovarian cancer cells, and a new biomarker that may open up more avenues for targeted therapies. The study, published in the journal Cell, was led by W…

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Oral Contraceptives Associated with Lower Ovarian Cancer Risk in BRCA Mutation Carriers

A study published in the American Journal of Obstetrics & Gynecology provides new insight into previously established research that oral contraceptive use is connected to lower ovarian cancer risk in the general population, by more closely…

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OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations

A long-running study from Dana-Farber Cancer Institute, published in Nature Cancer and co-funded by OCRA, has discovered that the antibiotic novobiocin is capable of targeting and killing tumor cells in laboratory cell lines and tumor models with…

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Seeking New Insights Into Origins of Ovarian Cancer | Meet a Scientist

“It’s kind of like how the Apollo mission to the moon gave us Velcro.” Dr…

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OCRA-Funded Research Uncovers New Checkpoint Mechanism, Potential New Therapeutic Target

New research from The Wistar Institute and Peter MacCallum Cancer Center has uncovered a previously unknown checkpoint mechanism for gene expression, that may open up new avenues for transcription-based targeted cancer therapies in the future…

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Large Study Suggests Ovarian Cancer Screening in General Public Doesn’t Save Lives

Results from a large British clinical trial, which involved more than 200,000 post-menopausal women who were followed for more than 15 years, showed that screening average-risk, asymptomatic women for ovarian cancer does not reduce deaths from the…

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