Research News

The Institute of Medicine Reports on Ovarian Cancer

The Institute of Medicine (IOM) recently released a report commissioned by Congress, Ovarian Cancers: Evolving Paradigms in Research and Care. The report provides an in-depth look at the state of ovarian cancer in the United States…

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Dose-dense Weekly Paclitaxel Does Not Increase PFS

(March 3, 2016) In a study published in the New England Journal of Medicine this week, researchers report that a dose-dense weekly paclitaxel regimen failed to improve progression-free survival in advanced ovarian cancer versus a conventional…

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Clinical Trial Highlight: Long-Term Survivor Study

Official Trial Name:  The Genomic, Epigenomic, and Psychosocial Characteristics of Long-Term Survivors of Ovarian Cancer – Recruitment…

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OCRF Research Illuminates Origins of PPM1D Mutations in Ovarian Cancer Patients

(February 24, 2016) Research led by Dr…

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Research News: Talcum Powder

The Ovarian Cancer Research Alliance provides information based on medical research and best practices. Research regarding a connection between the use of talcum powder and increased ovarian cancer risk is inconclusive…

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OCRF Research Defines How Satb1 Gene Goes from Helpful to Harmful in Ovarian Cancer

(February 22, 2016) Imagine a lighthouse on cancer cells that can tell the T-cells in our immune system precisely where to attack to stop cancer in its tracks. When working properly, that’s exactly what dendritic cells do…

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Increased Risk of Epithelial Ovarian Cancer associated with BRIP1 Gene

(January 27, 2016) A new study of 8,000 women reported in the Journal of the National Cancer Institute reports that carrying mutations in a gene called BRIP1 raised a woman’s chance of getting ovarian cancer in her lifetime to approximately…

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OCRF Research Finds Inherited Mutations in 18% with Ovarian Cancer

(Jan. 8, 2016) OCRF grantees Dr. Barbara Norquist and Dr…

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Study Results Show Ovarian Cancer Screening Doesn’t Save Lives; Researchers Optimistic About Future Results

(December 17, 2015) This morning in London, researchers announced the long-awaited final results of the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)…

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Under the Microscope: OCRF’s 2015 Research Progress Report

(12/14/15) | In 2015, OCRF grantees made several significant advances in the fight against ovarian cancer, including: Pinpointing two genes that trigger ovarian cancer Identifying a new therapeutic strategy for clear cell ovarian cancer Discovering…

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Our Response to the UKCTOCS ROCA & CA-125 Results

WASHINGTON — Today, the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) of the University College London released the results of its study to determine if the risk of ovarian cancer algorithm (ROCA), when used yearly in conjunction…

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Nintedanib Delays Progression of Advanced Ovarian Cancer

(December 4, 2015) According to the results of a phase III trial of over 1,000 women, women with advanced ovarian cancer gained significant delays in the progression of their disease when they were treated with the drug nintedanib plus…

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