Research News

OCRF Research Defines How Satb1 Gene Goes from Helpful to Harmful in Ovarian Cancer

(February 22, 2016) Imagine a lighthouse on cancer cells that can tell the T-cells in our immune system precisely where to attack to stop cancer in its tracks. When working properly, that’s exactly what dendritic cells do…

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Increased Risk of Epithelial Ovarian Cancer associated with BRIP1 Gene

(January 27, 2016) A new study of 8,000 women reported in the Journal of the National Cancer Institute reports that carrying mutations in a gene called BRIP1 raised a woman’s chance of getting ovarian cancer in her lifetime to approximately…

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OCRF Research Finds Inherited Mutations in 18% with Ovarian Cancer

(Jan. 8, 2016) OCRF grantees Dr. Barbara Norquist and Dr…

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Study Results Show Ovarian Cancer Screening Doesn’t Save Lives; Researchers Optimistic About Future Results

(December 17, 2015) This morning in London, researchers announced the long-awaited final results of the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)…

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Under the Microscope: OCRF’s 2015 Research Progress Report

(12/14/15) | In 2015, OCRF grantees made several significant advances in the fight against ovarian cancer, including: Pinpointing two genes that trigger ovarian cancer Identifying a new therapeutic strategy for clear cell ovarian cancer Discovering…

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Our Response to the UKCTOCS ROCA & CA-125 Results

WASHINGTON — Today, the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) of the University College London released the results of its study to determine if the risk of ovarian cancer algorithm (ROCA), when used yearly in conjunction…

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Nintedanib Delays Progression of Advanced Ovarian Cancer

(December 4, 2015) According to the results of a phase III trial of over 1,000 women, women with advanced ovarian cancer gained significant delays in the progression of their disease when they were treated with the drug nintedanib plus…

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OCRF Research Identifies Targetable Mutations in Low Grade Serous Ovarian Cancer

(December 2, 2015) Research funded in part by an OCRF grant to Rachel Grisham, MD has identified new, potentially targetable mutations in patients with low grade serous ovarian cancer. Dr…

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OCRF Research Offers Insight on How Ovarian Cancer Grows

(December 1, 2015) Research funded in part by Ovarian Cancer Research Fund, and published in PNAS, offers new insights into how ovarian cancer grows—and the potential to stop it…

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Better Outcomes for Ovarian Cancer Patients with History of Oral Contraceptive Use

(November 20, 2015) A study published in BMC Cancer demonstrates that ovarian cancer patients who had a history of oral contraceptive use had better outcomes than those who had not previously used them. Dr. Aminah Jatoi and co-author Dr…

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Ten-year Survival Not Associated with BRCA Mutation Status

(Nov. 19, 2016) In research published this month in Gynecologic Oncology, a group of Canadian researchers have found that long-term survival is not associated with BRCA mutation status in ovarian cancer patients…

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Meet OCRF’s 2016 Grantees

OCRF has awarded $5.2 million in new grants, bringing our total investment in ovarian cancer research to nearly $70 million…

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