Research News

The Overview: December 2021

This time of year always has us reflecting on what we’ve accomplished, what we hope to achieve in the future, and how we — with the support of the entire ovarian cancer community — can lean in even harder to our commitment…

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OCRA-Funded Research Identifies New “Master” Drug Targets for Ovarian Cancer

An interdisciplinary group of researchers from around the country analyzed tumor samples from nearly 10,000 patients with 34 types of cancer to reveal unique genetic switches associated with each tumor type…

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OCRA-Funded Study Points to New Approach to Improve Ovarian Cancer Treatment

The following is a press release from University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, and Magee-Womens Research Institute PITTSBURGH, Nov…

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The Overview: October 2021

Have we got a roundup in store! You heard from us a lot in September (thanks to you, we surpassed our Ovarian Cancer Awareness Month fundraising goal!) and there’s still so much to report … research progress, a brand new clinical trial…

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Study Finds Germline Ovarian Cancer Mutations Occur Equally in Black and White Patients

A recent study has shed more light on the demographics of hereditary ovarian cancer, and provides further data to suggest an urgent need for increased genetic counseling for potentially high-risk Black women, as well as increased genetic testing in…

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Finding the Story in the Data | Meet a Scientist

Sridevi Challa, PhD, an OCRA grantee at UT Southwestern, is on the receiving end of some major accolades…

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OCRA-Funded Study Identifies Role of Deubiquitinating Enzyme in Ovarian Cancer Progression

OCRA grantee Dr. Sumegha Mitra of Indiana University and colleagues have identified the mechanism by which a specific deubiquitinating enzyme known as UCHL1 promotes the growth of high-grade serous ovarian cancer in some patients…

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Groundbreaking Initiative Seeks to Accelerate Development of New Treatments with OCRA’s Support

LOS ANGELES – (BUSINESS WIRE)–Global Coalition for Adaptive Research (GCAR) announces a new clinical trial initiative, Ovarian CanceRxTM…

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OCRA-Funded Research Reveals New Ovarian Cancer Biomarker and Growth Mechanisms

Researchers at UT Southwestern have discovered a potential “Achilles’ heel” in ovarian cancer cells, and a new biomarker that may open up more avenues for targeted therapies. The study, published in the journal Cell, was led by W…

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Oral Contraceptives Associated with Lower Ovarian Cancer Risk in BRCA Mutation Carriers

A study published in the American Journal of Obstetrics & Gynecology provides new insight into previously established research that oral contraceptive use is connected to lower ovarian cancer risk in the general population, by more closely…

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OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations

A long-running study from Dana-Farber Cancer Institute, published in Nature Cancer and co-funded by OCRA, has discovered that the antibiotic novobiocin is capable of targeting and killing tumor cells in laboratory cell lines and tumor models with…

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Seeking New Insights Into Origins of Ovarian Cancer | Meet a Scientist

“It’s kind of like how the Apollo mission to the moon gave us Velcro.” Dr…

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