Research News

OCRA-Funded Research Breakthroughs in 2019

OCRA-funded scientists have been hard at work this year, uncovering breakthroughs in ovarian cancer prevention, diagnostics, and treatment that can save women’s lives…

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OCRA Research Reveals Two Cells of Origin for High Grade Ovarian Cancer

(December 3, 2019) The origins of high grade serous ovarian carcinoma (HGSOC) is a debated topic in the scientific community…

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OCRA-Funded Research Yields Insight into Clear Cell Ovarian Cancers

(November 13, 2019) A study recently published in Nature Communications and led by OCRA grantee Dr. Rugang Zhang showed that the ARID1A protein plays a fundamental role in ensuring correct chromosome segregation when the cells divide…

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IUD May Lower Risk of Developing Ovarian Cancer

(November 6, 2019) A recent research review conducted by a team at the University of Colorado Anschutz, and published this month by the American College of Obstetrics and Gynecology, found that use of an intrauterine device (IUD) was associated with…

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OCRA-Funded Research Explores New Pathways for Understanding Metastases

(October 30) In an effort to further understand disease initiation and progression, OCRA grantee Dr…

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PARP Inhibitor and Chemotherapy Combination Improves Progression-Free Survival

(October 7, 2019) Published recently in the New England Journal of Medicine, a group of investigators led by OCRA Scientific Advisory Committee member Dr…

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OCRA-Funded Research Elucidates New Immunotherapy Approach

(September 19, 2019) While harnessing the immune system has resulted in strong responses for a subset of cancer patients, the majority of patients have remained unresponsive to this approach…

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OCRA-Funded Research Points to Surrounding Tissues for Further Study

(September 10, 2019) Ovarian clear-cell carcinoma is an aggressive form of ovarian cancer.  Endometriosis is derived from the uterine endometrium and is a known risk factor for ovarian clear-cell carcinoma…

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OCRA-Funded Research Moves Immunotherapy Forward

(September 5, 2019) OCRA funded investigator Dmitriy Zamarin, MD, PhD contributed to a study that provides an intriguing hypothesis that mutation in genes like SMARCA4 may improve tumor recognition by the immune system…

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Should You Be Tested for BRCA Mutations? New Guidelines

(August 22, 2019) This week, The US Preventive Services Task Force published new recommendations on risk assessment, genetic counseling, and genetic testing for BRCA mutations and BRCA-related cancers…

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New Direction for Research: Microbiota

(August 20, 2019) A new direction for research in ovarian cancer was brought to light last month thanks to a study published in Lancet Oncology. Researchers led by Dr. Nuno R…

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OCRA Funded Research Reveals New Drug Therapy Combination

(July 26, 2019) OCRA grantee Michael Yaffe, MD, PhD, led a study published earlier this month in Cell Systems which found success targeting cancer cells by combining two existing classes of drugs. Dr…

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