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OCRFA Research Shows Novel Combination Therapy Effective in...

OCRFA Research Shows Novel Combination Therapy Effective in Ovarian Cancer

(December 20, 2017) Cell Reports published new research from the Wistar Institute, which looked at the potential benefits of a therapy that combines PARP inhibitors and BET inhibitors for ovarian cancer patients without BRCA mutations. The research was funded in part by an OCRFA grant to Rugang, Zhang, PhD. PARP inhibitors have already been approved … Continued

OCRFA’s Impact in 2017

OCRFA’s Impact in 2017

(December 14, 2017) For over two decades, you have made it possible for OCRFA to fund the most innovative and promising science, resulting in research breakthroughs that have advanced our understanding of ovarian cancer, how it starts and new treatment options, and you have enabled OCRFA to successfully advocate for federal research dollars and provide … Continued

OCRFA Funded Research Identifies Mechanism Underlying Ovari...

OCRFA Funded Research Identifies Mechanism Underlying Ovarian Cancer Development

(November 22, 2017) A recent paper published in the Journal of Clinical Investigation reports that a subset of ovarian cancers reduce the expression of a critical gene involved in recycling the cells’ proteins, known as ubiquitin B (UBB). Silencing the expression of a closely related gene, also in the ubiquitin family, that performs an identical … Continued

OCRFA Funded Study Discovers 3 Key Genes in Prevention and ...

OCRFA Funded Study Discovers 3 Key Genes in Prevention and Treatment of BRCA1 and BRCA2 Tumors

(October 19, 2017) BRCA1 and BRCA2 are among the most frequently mutated genes in ovarian cancer. Studies conducted in the past two decades have shown that BRCA1 and BRCA2 play an essential role in protecting DNA from lesions that can lead to tumor formation. However, the factors that cause DNA lesions in BRCA1- and BRCA2-deficient … Continued

OCRFA’s Response to Trump Administration’s Birth Cont...

OCRFA’s Response to Trump Administration’s Birth Control Coverage Rollback

(Oct. 11, 2017) Last week, the Trump Administration issued a regulation to immediately allow employers to deny insurance coverage for birth control on the basis of their own moral or religious objections, undermining the landmark benefit under the Affordable Care Act (ACA) that guarantees coverage for contraception without co-pays or cost-sharing. Audra Moran, President and … Continued

Folonari Wines Partners with OCRFA

Folonari Wines Partners with OCRFA

(September 8, 2017) Through its ongoing ‘AMORE, ITALIA, FOLONARI’ campaign, Folonari Wines has partnered this year with Ovarian Cancer Research Alliance. Joining forces with OCRFA gives Folonari a national platform to continue their fight against ovarian cancer with the ‘Time to Teal with Folonari’ campaign. Frederick Wildman and Sons will working together with its trade … Continued

Newk’s Eatery “Joins the Fight” Against O...

Newk’s Eatery “Joins the Fight” Against Ovarian Cancer with Fundraiser

(August 31, 2017) In answer to the persisting need for a cure to one of the deadliest diseases facing women today, Newk’s Eatery is calling on partners and patrons across its 115 restaurants to “Join the Fight” against ovarian cancer. During Ovarian Cancer Awareness Month this September, guests both dining in or ordering online are … Continued

OCRFA Funded Project Has Breakthrough on Therapeutic Approa...

OCRFA Funded Project Has Breakthrough on Therapeutic Approach for Rare Ovarian Cancer

(July 27, 2017) Earlier this week, in Nature Cell Biology, researchers at The Wistar Institute published their findings about a few strategies to treat clear cell carcinoma. Clear cell is a rare form of ovarian cancer that does not usually respond well to platinum-based chemotherapy, which leaves patients with few options. In most cases of … Continued

Leading ovarian cancer organization announces 2017 honorees

Leading ovarian cancer organization announces 2017 honorees

Largest private funder of ovarian cancer research recognizes top researchers and community leaders NEW YORK — Today, Ovarian Cancer Research Alliance (OCRFA), the nation’s leading ovarian cancer research, advocacy and patient support organization, announces this year’s winners of its research and survivor awards at its annual conference. OCRFA honors two outstanding researchers for their cutting-edge … Continued

OCRFA Earns 4-Star Rating from Charity Navigator

OCRFA Earns 4-Star Rating from Charity Navigator

(July 6, 2017) OCRFA is pleased to announce we have once again earned a 4-star rating from Charity Navigator, America’s largest independent charity evaluator. This rating, the highest awarded by Charity Navigator, demonstrates OCRFA’s continued commitment to maintaining responsible fiscal management practices, as well as transparency and accountability, as we continue to strive toward a cure for ovarian … Continued

Action Alert: Protect Federal Funding for Ovarian Cancer Re...

Action Alert: Protect Federal Funding for Ovarian Cancer Research

The White House has released a proposed budget for FY2018 that makes drastic cuts to the budgets for the National Institute of Health (NIH) and Centers for Disease Control and Prevention (CDC). These cuts would reduce the NIH budget by 20% and threaten to halt breakthrough medical research advancements and delay life-saving cures. The proposed … Continued

OCRFA Funded Study Determines the Importance of Tumor Antigen

OCRFA Funded Study Determines the Importance of Tumor Antigen

(May 2, 2017) A study, published in Gynecologic Oncology, revealed the importance of tumor antigen NY-ESO-1 for ovarian cancer patients. This tumor antigen, although not normally found in healthy cells, is very prevalent in tumors such as epithelial ovarian cancers. Over the course of the 14 year study, Roswell Park tested 1,000 ovarian cancer patients … Continued

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