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World Ovarian Cancer Coalition Releases Every Woman Study Report

World Ovarian Cancer Coalition Releases Every Woman Study Report

(October 25, 2018) Through a series of surveys, interviews, and literature reviews the World Ovarian Cancer Coalition produced a report that detailed their findings and recommendations. Their study spanned the world, 44 countries, and collected responses from 1531 women. Of those women, all had been diagnosed with ovarian cancer on or after January 2013, and … Continued

Study Looks at Long-term Survival Trends in Ovarian Cancer

Study Looks at Long-term Survival Trends in Ovarian Cancer

(October 19, 2018) A retroactive study using SEER, or Surveillance, Epidemiology, and End Results, looked at the trends in ovarian cancer from 1983 to 2012. In almost 3 decades, the incidence of ovarian cancer per 100,000 fell from 13.7 to 10.8 and the median survival increased from 34 months to 52 months. When this survival … Continued

OCRA Funded Research Reveals Immune Suppression in Ovarian Cancer

OCRA Funded Research Reveals Immune Suppression in Ovarian Cancer

(October 15, 2018) This month in Nature, researchers from Weill Cornell published a study that helps to explain why the body’s natural immune response struggles to fight back against ovarian cancer. Using ovarian tumors from humans and mice, they found that T cells, vital to destroying cancerous cells, are inhibited because of the tumor’s effect … Continued

Baby Aspirin Associated with Lower Risk of Ovarian Cancer

Baby Aspirin Associated with Lower Risk of Ovarian Cancer

(October 9, 2018) A study, published in JAMA Oncology, followed about 200,000 women over the course of 25 years in order to track their use of analgesics. A little over one-thousand of those women developed epithelial ovarian cancer within that time frame. Although researchers didn’t find any significant differences in risk when they evaluated aspirin … Continued

OCRFA Funded Research Identifies Biomarker Linked to HGSOC Treatment and Survival Outcomes

OCRFA Funded Research Identifies Biomarker Linked to HGSOC Treatment and Survival Outcomes

(September 21, 2018) In an international collaboration funded in part by OCRFA, published recently in Cell, researchers used proteomics, the large-scale study of proteins, to identify an important indicator for treatment and disease-free survival in patients with high grade serous ovarian cancer. The biomarker, known as CT45, is associated with better response to chemotherapy and … Continued

Big Strides Made in Identifying More BRCA1 Mutations

Big Strides Made in Identifying More BRCA1 Mutations

(September 19, 2018) Researchers at the University of Washington recently made a breakthrough in identifying and confirming variants of the BRCA1 mutation, a gene mutation that increases a woman’s risk of breast and ovarian cancers. Although the most common BRCA1 and BRCA2 mutations are already known to increase risk, there are thousands of variants of … Continued

Exploring the Importance of Glycogen in Cancer Metastasis

Exploring the Importance of Glycogen in Cancer Metastasis

(September 14, 2018) A study published in Cell Metabolism explores the use of glycogen by ovarian cancer tumor cells, specifically in an area where metastasis happens quickly, the omentum. The omentum, or fatty tissue in the abdomen, is used by the cancer cells for the energy-heavy fat cells to grow. Once that energy source is … Continued

New Clues on the Origins of Ovarian Cancer

New Clues on the Origins of Ovarian Cancer

(August 30, 2018) Researchers at Brigham and Women’s Hospital in Boston have found new clues to the origin of high-grade serous carcinoma (HGSC). The majority of women who are diagnosed with ovarian cancer have HGSC, and up to 90 percent of those cases go undetected and undiagnosed until the cancer has spread. Previous studies showed the … Continued

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