A new approach to monitoring CA-125, using an algorithm that looks at its change over time, is more effective at identifying ovarian cancer earlier than using a single-threshold number.
In an analysis of more than 4,000 women with ovarian cancer, it appears that some hormonal and reproductive factors may affect tumor aggressiveness. The study showed that increased age was associated with greater risk of rapidly fatal disease use of oral contraceptives was associated with a decreased risk of rapidly fatal disease increased parity (having … Continued
A study of 149 women with platinum sensitive ovarian cancer, half treated with carboplatin and paclitaxel or gemcitabine, half with that treatment plus pertuzumab, showed that the addition of pertuzumab to chemotherapy did not significantly increase progression free survival (PFS). However, the drug was described as “well-tolerated” and did not appear to increase the risk … Continued
OCRF receives record number of research grant applications; launches national patient support program with new educational grants New York, NY January 10, 2013 — Ovarian Cancer Research Fund (OCRF) has awarded over $5.9 million in scientific research grants for ovarian cancer this year. Additionally, two educational and support grants totaling $100,000 were given to new … Continued
OCRF has awarded nearly $6 million in grants for ovarian cancer research this year. After receiving over 170 applications – the highest number in its history, for the second year in a row – OCRF and its prestigious Scientific Advisory Committee endeavored first and foremost to fund the best science. The Committee evaluated each proposal … Continued
1/09/2013 Analyzing DNA from Pap smears could help detect endometrial and ovarian cancer, a new study published Jan. 9, 2013 in Science Translational Medicine reports. OCRF Scientific Advisory Committee member (and former grantee) Doug Levine, MD, was among the authors of the article, which was highlighted on the cover of the journal. The routine Pap smear, which allows … Continued
1/3/2013 In the most recent edition of the Journal of Clinical Oncology, researchers in the UK published preliminary results from the United Kingdom Familial Ovarian Cancer Screen Study, a large trial testing the hypothesis that ovarian cancer screening may benefit women at familial risk. Results showed that annual screening did lead to diagnosis at an earlier stage, … Continued
Lindsay Avner founded Bright Pink in 2007, shortly after she learned that she carried a mutation in the BRCA gene. Just 22 years old when she was tested, Lindsay realized that she had nowhere to turn for advice on coping with her increased risk of breast and ovarian cancer. “There was nothing for women who … Continued
01/01/2013 Previous studies have suggested that BRCA mutation carriers with ovarian cancer have better survival rates than women who are not carriers. Researchers in Canada and the US sought to investigate long-term survival (10 years post diagnosis) in BRCA mutation carriers. Their results show that “for women with invasive ovarian cancer, the short-term survival advantage of … Continued
12/14/2012 | Mindy Gray was devastated by the passing of her beloved older sister, Faith Basser. But she turned loss into legacy and hurt into hope this year when she and her husband Jon founded the Basser Research Center at the University of Pennsylvania in honor of her sister who succumbed to ovarian cancer at … Continued
12/11/12 | In 2012, hardworking, dedicated OCRF scientists made significant advances in the fight against ovarian cancer. Below is just a sample of some of the exciting discoveries made by OCRF-funded researchers this year. With your generous support, OCRF grantees have: Thank you for supporting our mission to fund scientific research that will lead to … Continued
Metformin, a drug used to treat diabetes and polycystic ovarian syndrome (PCOS), may increase survival for women with ovarian cancer. A study of 239 women with ovarian cancer divided them into two arms: those with diabetes who were taking metformin and those who did not have diabetes. More women with diabetes lived longer. Read the … Continued
Get email updates about research news, action alerts, and ways to join the fight.
