Search Results for “brca” - Page 10 - Ovarian Cancer Research Alliance

Feb 28, 2013

Press Release: Cancer Groups Praise Coverage of Genetic Counseling and Testing Under Affordable Care Act, Urge Coverage of Other Vital Services

...and ovarian cancer risk in women with a family history of cancer. Breast and ovarian cancers have been linked to mutations in the BRCA1 and BRCA2 genes. The Ovarian Cancer...

Jun 17, 2025

OCRA Featured in Fortune on Surgery That Reduces Ovarian Cancer Risk

...does not affect hormone levels or ovarian function. Those with genetic risk—such as a BRCA1 or BRCA2 mutation—may want to consider salpingectomy even without a separate planned surgery. Explore OCRA’s...

What is CA-125? Understanding the Blood Test

Learn what CA-125 is, how this ovarian cancer biomarker is used, and why it’s not a screening tool. Explore its role in diagnosis, monitoring, and recurrence.

Detection & Diagnosis

Explore the role of imaging exams, the CA-125 blood test, and surgical biopsy in detecting ovarian cancer. Learn about key steps to take in your health journey.

Apr 21, 2017

OCRFA Research Finds New Genetic Variants Linked to Ovarian Cancer

A study published in Nature Genetics has identified nine new susceptibility loci, or disease-associated alleles, for different epithelial ovarian cancer (EOC) histotypes and three susceptibility loci within BRCA1 and 2...

Nov 12, 2020

What’s New in Ovarian Cancer Research and Treatment

...for ovarian cancer continues to show promise. The SOLO-1 trial, for instance, illustrates that the PARP inhibitor olaparib can significantly improve progression-free survival for patients with an inherited BRCA mutation....

Dec 22, 2014

FDA Approves Olaparib for Ovarian Cancer

(December 19, 2014) The U.S. Food and Drug Administration (FDA) has approved AstraZeneca’s Olaparib (Lynparza) for advanced, BRCA-mutated ovarian cancer, the first approval of a drug in the PARP (poly...

Dec 11, 2017

The Relationship Between Cytotoxic CD8 Tumor-Infiltrating Lymphocytes and Overall Survival in High Grade Serous Ovarian Cancer

...TILs, as well as BRCA 1 mutation carriers. BRCA 2 carriers were not observed to benefit from them. The study authors concluded, “that the extent of infiltration is prognostic, not...

Apr 14, 2015

Rucaparib Receives Breakthrough Therapy Designation from FDA

...of platinum-sensitive ovarian cancer, specifically in patients with tumors that have BRCA mutations and other DNA deficiencies commonly referred to as “BRCA-like.” An FDA-designated “breakthrough therapy” is a drug to...

Jun 29, 2021

What is Lynch Syndrome?

Inherited gene mutations, such as BRCA 1 and BRCA 2, can increase the risk of developing ovarian cancer as well as uterine (endometrial) cancer. Some of these mutations, which affect...

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