Most High Risk Women Aren't Aware of Ovarian Cancer Risk
…in BRCA1 or BRCA2 are at substantially elevated risk for ovarian cancer. To understand what percentage of women with high risk family histories know their risk is elevated, researchers at…
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RAD51Â Mutations Confer Moderate Risk of Ovarian Cancer
…EOC and 2,772 controls from a case-control study, as well as 2,000 unaffected BRCA1/2-negative women from the U.K. Familial Ovarian Cancer Screening Study. OCRF SAC member Kunle Odunsi, MD, PhD,…
A New Generation Finds Purpose in Fundraising to Fight Ovarian Cancer
…and Elizabeth on the day Elizabeth was tested for BRCA mutations An opportunity to contribute came about when Emma started making bracelets earlier this year and a few friends expressed…
A Rogue Parakeet and a Reason for Hope
…impacted your family? Cancer does not just affect the patient; it includes family and friends. Even though I didn’t have a BRCA1 or BRCA2 mutation that could increase ovarian cancer…
USPSTF Does Not Recommend Ovarian Cancer Screening for General Population
…published on July 18th, does not apply to women who are positive for BRCA1 and BRCA2 genetic mutations, who have a higher risk of developing ovarian cancer. There are two…
Jeff Boyd, PhD, Appointed Chair of OCRF Scientific Advisory Committee
…ovarian cancer, as well as other women’s cancers. He has helped define the role of tumor suppressors and oncogenes in these malignancies, most notably the p53, BRCA1 and BRCA2 tumor…
Multimodal Study Uses Machine Learning to Improve Risk-Stratification of HGSOC
…in the TGCA-OV set. To gain insights around treatment resistance, particular attention was paid to homologous recombination-deficient (HRD) disease status, presence of BRCA1 or BRCA2 mutations, and associated response to…
Screening High-Risk Women Catches More Early Stage Ovarian Cancers
…primary recommendation for women of high risk, specifically after having children, before the age of 40 for BRCA1 carriers, and before 45 years of age for BRCA2 carriers. “Up until…
Study Reveals New Mechanism of Action for PARP Inhibitors
…in their ability to kill cancer cells. PARP inhibitors are a class of drugs that have shown promising results against ovarian cancer in women with BRCA1 and BRCA2 gene mutations….
Highlights: 2022 Annual Meeting of the Society of Gynecologic Oncology (SGO)
…cancers respond to particular treatments or better tolerate treatment at a lower starting dose (predictive biomarkers). Biomarkers can be mutation carrier status (BRCA1 or 2+), molecular characteristics of tumors (HRD,…
Partner Member Profile: Hope for Heather
…in honor of Rebecca Hafner, who lost her life to ovarian cancer. They partner with breast cancer organizations to hold combined events, raising awareness about the BRCA1 and BRCA2 inherited…
For Some, Statin Use Can Decrease the Risk of Ovarian Cancer
…seen in women who were BRCA1 or BRCA2 positive or women who were premenopausal. 11 on For Some, Statin Use Can Decrease the Risk of Ovarian Cancer The best outcomes…