Search Results for “brca” - Page 10 - Ovarian Cancer Research Alliance

May 4, 2020

Niraparib Receives FDA Approval as First-Line Maintenance Therapy for Advanced Ovarian Cancer

...regardless of BRCA mutation status. Niraparib was first approved by the FDA for treatment of recurrent ovarian cancer in 2017. This most recent approval means ovarian cancer patients do not...

Feb 28, 2013

Press Release: Cancer Groups Praise Coverage of Genetic Counseling and Testing Under Affordable Care Act, Urge Coverage of Other Vital Services

...and ovarian cancer risk in women with a family history of cancer. Breast and ovarian cancers have been linked to mutations in the BRCA1 and BRCA2 genes. The Ovarian Cancer...

What is CA-125? Understanding the Blood Test

Learn what CA-125 is, how this ovarian cancer biomarker is used, and why it’s not a screening tool. Explore its role in diagnosis, monitoring, and recurrence.

Research Prizes

Discover OCRA’s Cancer Research Prizes, recognizing outstanding research contributions and honoring individual scientific achievement.

Detection & Diagnosis

Explore the role of imaging exams, the CA-125 blood test, and surgical biopsy in detecting ovarian cancer. Learn about key steps to take in your health journey.

Aug 11, 2025

Why I Give: Continuing the Rivkin Center Legacy with Ovarian Cancer Research Alliance

...tested negative for BRCA1 and BRCA2 mutations —inherited genetic mutations that are known to elevate risk—but Kim knows there is more to discover. That’s part of the research we need:...

Apr 21, 2017

OCRFA Research Finds New Genetic Variants Linked to Ovarian Cancer

A study published in Nature Genetics has identified nine new susceptibility loci, or disease-associated alleles, for different epithelial ovarian cancer (EOC) histotypes and three susceptibility loci within BRCA1 and 2...

Nov 12, 2020

What’s New in Ovarian Cancer Research and Treatment

...for ovarian cancer continues to show promise. The SOLO-1 trial, for instance, illustrates that the PARP inhibitor olaparib can significantly improve progression-free survival for patients with an inherited BRCA mutation....

Dec 22, 2014

FDA Approves Olaparib for Ovarian Cancer

(December 19, 2014) The U.S. Food and Drug Administration (FDA) has approved AstraZeneca’s Olaparib (Lynparza) for advanced, BRCA-mutated ovarian cancer, the first approval of a drug in the PARP (poly...

Dec 11, 2017

The Relationship Between Cytotoxic CD8 Tumor-Infiltrating Lymphocytes and Overall Survival in High Grade Serous Ovarian Cancer

...TILs, as well as BRCA 1 mutation carriers. BRCA 2 carriers were not observed to benefit from them. The study authors concluded, “that the extent of infiltration is prognostic, not...

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