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OCRF Research Illuminates Origins of PPM1D Mutations in Ova...

OCRF Research Illuminates Origins of PPM1D Mutations in Ovarian Cancer Patients

(February 24, 2016) Research led by Dr. Elizabeth Swisher at the University of Washington, funded in part by OCRFA and published this month in JAMA Oncology, shows that mutations in the gene PPM1D in women with ovarian cancer are the result of aging and chemotherapy exposure. Read the abstract in JAMA Oncology. Previously, somatic mosaic … Continued

OCRF Research Defines How Satb1 Gene Goes from Helpful to H...

OCRF Research Defines How Satb1 Gene Goes from Helpful to Harmful in Ovarian Cancer

(February 22, 2016) Imagine a lighthouse on cancer cells that can tell the T-cells in our immune system precisely where to attack to stop cancer in its tracks. When working properly, that’s exactly what dendritic cells do. They break down cancer cells into antigens that T-cells can “read” and know to attack while sparing healthy … Continued

Strength in Numbers: OCRF and OCNA Unite to Form OCRFA

Strength in Numbers: OCRF and OCNA Unite to Form OCRFA

As of January 2016, we are pleased to announce we are joining together to form Ovarian Cancer Research Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting women and their families.

Meet the New OCRFA!

Meet the New OCRFA!

The Ovarian Cancer National Alliance and Ovarian Cancer Research Fund have led the way in advocacy, research and support for patients and their families for over 22 years. We are pleased to announce we are joining together to form Ovarian Cancer Research Alliance (OCRFA), the largest global organization dedicated to advancing ovarian cancer research while supporting … Continued

Ovarian Cancer National Alliance and Ovarian Cancer Researc...

Ovarian Cancer National Alliance and Ovarian Cancer Research Fund Announce Merger, Formation of Ovarian Cancer Research Alliance

Merger to create largest global ovarian cancer policy advocacy and research organization January 26, 2016 — Today, two of the nation’s foremost ovarian cancer policy advocacy and research organizations, the Ovarian Cancer National Alliance and Ovarian Cancer Research Fund announced a merger, forming the Ovarian Cancer Research Alliance (OCRFA). This move comes at a critical … Continued

OCRF Research Finds Inherited Mutations in 18% with Ovarian...

OCRF Research Finds Inherited Mutations in 18% with Ovarian Cancer

(Jan. 8, 2016) OCRF grantees Dr. Barbara Norquist and Dr. Elizabeth Swisher were part of a team that recently released a study which investigated the occurrence, and role of, inherited cancer associated genes in a randomly selected population of women diagnosed with ovarian cancer. The OCRF-supported study, published late last month in JAMA Oncology, found … Continued

Under the Microscope: OCRF’s 2015 Research Progress R...

Under the Microscope: OCRF’s 2015 Research Progress Report

(12/14/15) | In 2015, OCRF grantees made several significant advances in the fight against ovarian cancer, including: These discoveries are the direct result of generous donations from people like you. Progress is made every day, and the future is full of promise – with even more important successes to come. Thank you for supporting cutting-edge … Continued

OCRF Research Identifies Targetable Mutations in Low Grade ...

OCRF Research Identifies Targetable Mutations in Low Grade Serous Ovarian Cancer

(December 2, 2015) Research funded in part by an OCRF grant to Rachel Grisham, MD has identified new, potentially targetable mutations in patients with low grade serous ovarian cancer. Dr. Grisham is a medical oncologist at Memorial Sloan Kettering Cancer Center in New York and is a 2014 recipient of the Liz Tilberis Early Career … Continued

OCRF Research Offers Insight on How Ovarian Cancer Grows

OCRF Research Offers Insight on How Ovarian Cancer Grows

(December 1, 2015) Research funded in part by Ovarian Cancer Research Fund, and published in PNAS, offers new insights into how ovarian cancer grows—and the potential to stop it. Can any cancer cell form another tumor, or is it only select cancer stem cells that give rise to new cancer cells? The answer, a new … Continued

Meet OCRF’s 2016 Grantees

Meet OCRF’s 2016 Grantees

OCRF has awarded $5.2 million in new grants, bringing our total investment in ovarian cancer research to nearly $70 million.

OCRF Research Explains Limits of Cancer Immunotherapy Drugs

OCRF Research Explains Limits of Cancer Immunotherapy Drugs

A new study of ovarian cancer cells from the University of Michigan Comprehensive Cancer Center, funded in part by an OCRF grant to Dr. Weiping Zou, reveals molecular changes within the tumor that prevent immunotherapy drugs from killing off the cancer.  The research was published in Nature. Immunotherapy treatments have proven wildly successful in treating … Continued

New Ovarian Cancer National Alliance research finds state l...

New Ovarian Cancer National Alliance research finds state lawmakers have power to dramatically improve access to ovarian cancer care and outcomes for the 21,000 women diagnosed each year

For Immediate ReleaseSeptember 23, 2015 New Ovarian Cancer National Alliance research finds state lawmakers have power to dramatically improve access to ovarian cancer care and outcomes for the 21,000 women diagnosed each year WASHINGTON, D.C. — Today, the Ovarian Cancer National Alliance (OCNA) released groundbreaking new data in its report “50 States of Teal: Ovarian … Continued

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