OCRF Research Sheds Light on Ovarian Cancer Origins in BRCA...
OCRF Research Sheds Light on Ovarian Cancer Origins in BRCA Mutation Carriers
A team of current and former OCRF grantees at Brigham and Women’s Hospital, Harvard Medical School and Dana-Farber Cancer Institute has developed genetically engineered mouse models of high-grade serous ovarian cancer that shed light on the pathogenesis of ovarian cancer for BRCA1/2 mutation carriers. These models, which target the cell of origin (fallopian tube secretory cells) and recreate key genetic … Continued