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Dogs Smell Ovarian Cancer Tissue

Dogs Smell Ovarian Cancer Tissue

Two dogs at the University of Pennsylvania’s Penn Vet Working Dog Center are learning how to smell tissue that is in early stages of ovarian cancer.  The dogs have been able to smell the cancerous tissue 100% of the time.  The dogs are part of an interdisciplinary research project to help scientists discover a chemical … Continued

Time Interval from Surgery to Chemo Impacts Prognosis in Ov...

Time Interval from Surgery to Chemo Impacts Prognosis in Ovarian Cancer

Researchers in Austria investigated whether the time interval from surgery to start of chemotherapy has an impact on clinical outcome in patients with advanced serous ovarian cancer. Data from 191 patients with stage III or IV ovarian cancer who underwent surgery followed by platinum-based chemotherapy were analysed.  The results, which were published in Gynecologic Oncology on … Continued

Ovarian Cancer Therapies in Development

Ovarian Cancer Therapies in Development

Dr. Coleman, a member of the Alliance’s Scientific and Medical Advisory Board, conducted an interview on ovarian cancer therapies for the Cancer Network. He discussed the heterogeneity of ovarian cancer, angiogenesis inhibitors and new drugs in the pipeline. The full interview can be found here

Analysis Points to New Cell Lines as Tumor Models for Ovari...

Analysis Points to New Cell Lines as Tumor Models for Ovarian Cancer Research

Research published online last week in Nature Communications suggests that some of the cell lines most frequently used to study high-grade serous ovarian cancer (HGSOC) may not be the best.  OCRF grantee and SAC member Douglas Levine, MD was one of the authors of the paper. Cell lines derived from tumor tissue are the most … Continued

Progesterone and Estrogen Receptors are Prognostic Biomarke...

Progesterone and Estrogen Receptors are Prognostic Biomarkers for Some Ovarian Cancers

In an article published last week in The Lancet, an international group of investigators examined whether ovarian cancer tumors’ expression of the progesterone receptor (PR) and estrogen receptor (ER) was associated with survival in various subtypes of ovarian cancer.  To date, few biomarkers of ovarian cancer prognosis have been established. The study, which included 2,933 women, … Continued

Family History of Breast Cancer but no Genetic Mutation Doe...

Family History of Breast Cancer but no Genetic Mutation Does Not Raise Risk of Ovarian Cancer

Women with a family history of breast cancer but no BRCA1/2 mutation were found to be at average risk for developing ovarian cancer. The prospective study of 8005 women from a breast cancer family history clinic found that women with a BRCA2 mutation had a 17-times higher risk of developing ovarian cancer than average, and … Continued

OCRF Talk with Lin Zhang, M.D.

OCRF Talk with Lin Zhang, M.D.

In an interview, 3-time grantee Dr. Zhang discusses his research and what it means to receive an award from OCRF.

Report from ASCO 2013–What's New in Ovarian Canc...

Report from ASCO 2013–What's New in Ovarian Cancer Research

We recently returned from the annual meeting of the American Society of Clinical Oncology (ASCO), an annual event that gathers thousands of cancer researchers from around the world. Many new studies on or related to ovarian cancer were presented at this year’s ASCO meeting. Click here to read a summary of ovarian cancer research from … Continued

Supreme Court Strikes Down BRCA Gene Patents

Supreme Court Strikes Down BRCA Gene Patents

In a unanimous ruling issued June 13, 2013, the US Supreme Court ruled that private companies do not have the right to patent human genes. In Association for Molecular Pathology et al. v. Myriad Genetics, the court considered the validity of patents held by the Utah-based company Myriad Genetics for the BRCA1 and BRCA2 genes, which … Continued

June 2013 SNMMI Meeting

June 2013 SNMMI Meeting

Society for Nuclear Medicine and Molecular Imaging (SNMMI) Advocate Report from Laurel Pracht As a member of the SNMMI Advocate Advisory Board, formed in 2010 to better bridge the gap between the patient and nuclear medicine communities, I represent the ovarian patient community. Other diseases, including cancer, brain and heart disease are represented as well.  … Continued

Press Release: Ovarian Cancer Advocates Praise Supreme Cour...

Press Release: Ovarian Cancer Advocates Praise Supreme Court Decision on Gene Patents

Ruling Will Give Women More Options to Learn About Genetic Risk Washington, DC—The Supreme Court ruled today that a company cannot patent naturally occurring genes, including isolated gene segments, overturning a decision made by the United States Court of Appeals for the Federal Circuit in August 2012, which upheld a patent claim on the BRCA1 … Continued

New Meta-Analysis of Oral Contraception and Risk of Ovarian...

New Meta-Analysis of Oral Contraception and Risk of Ovarian Cancer

A new meta-analysis of more than 6000 studies shows that oral contraceptives significantly reduce the risk of ovarian cancer. The risk reduction increases proportionally with duration of use. See the abstract here

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