08/23/2012 According to a new study published in Cancer Research, Australian researchers have identified a gene that plays a significant role in the development of high-grade serous ovarian cancer tumors becoming resistant to liposomal doxorubicin (commonly known as Doxil), which is commonly used to treat recurrent ovarian cancer. Investigating the changes in a tumor from … Continued
08/23/2012 Reported online last week in Science Translational Medicine, researchers at MIT and Harvard used nanoparticles to demonstrate the nanoparticles that target a protein called ID4 can reduce ovarian cancer tumors in mice. Researchers hope that this approach could help speed the development of new drugs. As new technology allows researchers to sequence cancer cell … Continued
A study of 637 Japanese women with ovarian, fallopian or primary peritoneal cancer showed that dose dense chemotherapy provided a benefit. The standard of care arm provided chemotherapy every three weeks, the dose dense arm provided one of the drugs every week and the other every three weeks. Women who were on the dose dense … Continued
A study of approximately 2700 women showed that women who used fertility drugs did not have a higher risk of ovarian cancer, except for women who used fertility drugs and never got pregnant. Read the full abstract here.
A small retrospective study of women receiving taxane therapy for breast or ovarian cancer while pregnancy showed no statistically significant outcomes in maternal or fetal health. Read the abstract here
08/09/2012 Research investigating the efficacy of screening women with a two-step screening strategy using CA125 and transvaginal sonogram (TVS) is ongoing, as are efforts to identify better biomarkers to identify the disease. In this context, researchers conducted a study evaluating the hypothetical impact on mortality, as well as the cost effectiveness of screening women at … Continued
The L.A. Times published an editorial July 29 summing up years of data showing that aggressively screening and treating people for cancer does not always benefit them. The editorial also points out that population based studies may not apply to people with known risk factors, like a family history of breast/ovarian cancer. The editorial also … Continued
According to a study of 186 women with ovarian cancer, women with high levels of emotional support lived longer than women without them. The study also suggests that a high degree of “instrumental support” – that is, tangible assistance – did not have any effect on survival. Read the abstract here
07/19/2012Research published July 16th in the Journal of Clinical Oncology shows that greater social attachment was associated with a lower likelihood of death for ovarian cancer patients. A group of researchers, including senior author and OCRF grantee Anil Sood, MD examined how social support related to long term survival. Two types of social support were … Continued
07/18/2012 A study published in Cancer Epidemiology, Biomarkers, and Prevention this month re-confirms that there is no link between use of fertility drugs and an elevated risk of ovarian cancer. While in the past studies on this subject have produced conflicting results, this study adds to the increasing body of work showing that use of … Continued
A study of 219 ovarian cancer survivors showed that those who did “regular exercise and yoga had higher scores in physical functioning, fewer limitations with physical and emotional health, less pain, and more vitality than survivors who reported participating in regular exercise only.” Read the full abstract here
06/25/2012 Writing in the Journal of Clinical Oncology, Australian researchers suggest because BRCA mutation status impacts survival and treatment response, all women with nonmucinous ovarian cancer, regardless of family history, should be offered BRCA1/2 mutation testing. Researchers from the Peter MacCallum Cancer Centre in East Melbourne, Australia, screened 1,001 women with ovarian cancer to investigate … Continued
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