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Draft USPSTF Statement Recommends Against Ovarian Cancer Sc...

Draft USPSTF Statement Recommends Against Ovarian Cancer Screening

04/11/2012   In a draft statement released April 11, 2012, the U.S. Preventive Services Task Force (USPSTF) again stated that screening average-risk women for ovarian cancer does more harm than good. The USPSTF, an independent volunteer panel of non-government experts in prevention and evidence-based medicine, is composed of primary care providers (such as internists, pediatricians, family physicians, gynecologists/obstetricians, … Continued

Updates from the Society of Gynecologic Oncology Meeting

Updates from the Society of Gynecologic Oncology Meeting

04/03/2012 Members of OCRF’s senior staff and Scientific Advisory Committee recently attended the Society of Gynecologic Oncology (SGO) Annual Meeting on Women’s Cancer in Austin, TX. Now in its 43rd year, the Annual Meeting on Women’s Cancer continues to be the premier educational activity for women’s cancer care professionals. Data Confirm PARP Inhibitor Slows Ovarian … Continued

OCRF Invited to Participate in Important New National Resea...

OCRF Invited to Participate in Important New National Research Initiative

03/06/2012   The U.S. Preventive Services Task Force (USPSTF), an independent volunteer panel of non-government experts in prevention and evidence-based medicine, is composed of primary care providers (such as internists, pediatricians, family physicians, gynecologists/obstetricians, and nurses). This prestigious group conducts rigorous scientific reviews of a broad range of clinical preventive health care services (such as screening, counseling, … Continued

OCRF Research Defines Association Between Ovarian Cancer an...

OCRF Research Defines Association Between Ovarian Cancer and Endometriosis

02/22/2012   Research by a team of scientists funded by OCRF has shown that there is an association between invasive ovarian cancer and endometriosis.  The research was reported on February 22nd in Lancet Oncology. The Ovarian Cancer Association Consortium, a collaborative created with the support of OCRF and led by grantee Dr. Andrew Berchuck, conducted an analysis … Continued

OCRF Research Provides Further Evidence that Ovarian Cancer...

OCRF Research Provides Further Evidence that Ovarian Cancer Originates in Fallopian Tube

02/16/2012   Work funded by Ovarian Cancer Research Fund has shown that the high-grade serous ovarian cancer arises in the fallopian tube of mice that lack two specific genes. The report appeared online this week in the journal Proceedings of the National Academy of Sciences. Little is known about how ovarian cancer starts and spreads. Recent … Continued

New Study Evaluates Usefulness of New Symptom Indices

New Study Evaluates Usefulness of New Symptom Indices

01/24/2012 The use of symptom indices to identify patients with symptoms associated with ovarian cancer who may need further screening is increasing in both the UK and the US in an attempt to promote earlier diagnosis, but these indices may need to be reassessed in order to help better detect cancer, according to a study … Continued

OCRF Researchers Discover Genomic Complexity and AKT Depend...

OCRF Researchers Discover Genomic Complexity and AKT Dependence in Serous Ovarian Cancer

01/20/2012                Dr. Doug Levine and Dr. Carol Aghajanian, both recipients of OCRF grants, were part of a project recently published in Cancer Discovery that studied AKT inhibition in ovarian cancer cell lines with various mechanisms of AKT pathway activation. Researchers found that some cell lines were responsive to AKT inhibitors, but depended greatly on other, co-existent, … Continued

Meet OCRF’s 2012 Grantees

Meet OCRF’s 2012 Grantees

OCRF has awarded $5.4 million in grants for ovarian cancer research this year. After receiving over 100 applications – the highest number in its history – OCRF and its prestigious Scientific Advisory Committee endeavored first and foremost to fund the best science. The Committee evaluated each proposal through intensive peer review, and selected a sound … Continued

Ovarian Cancer Research Fund Awards $5.4 Million in 2012 Re...

Ovarian Cancer Research Fund Awards $5.4 Million in 2012 Research Grants

OCRF receives record number of grant applications; continues to fund the best science New York, NY January 3, 2012— Ovarian Cancer Research Fund (OCRF) has awarded $5.4 million in grants for ovarian cancer research this year. After receiving over 100 applications – the highest number in its history – OCRF and its prestigious Scientific Advisory … Continued

New Genetic Mutation Increases Risk of Ovarian Cancer

New Genetic Mutation Increases Risk of Ovarian Cancer

08/17/2011Researchers in the United Kingdom have discovered a new genetic mutation that increases the risk for ovarian cancer.  This major finding was published online in the journal Nature Genetics on August 7th. Much like the BRCA1 and BRCA2 mutations, which were discovered in the 1990s and which also increase a woman’s risk for ovarian cancer, … Continued

Researchers Create Genetic "Map" of Ovarian Cancer

Researchers Create Genetic "Map" of Ovarian Cancer

In a paper published on June 30, 2011 in the journal Nature, researchers working as part of The Cancer Genome Atlas (TCGA) Research Network report that they have created a genetic “map” of ovarian cancer.  This important work, which is the largest study of any tumor type to date, will help researchers better understand the … Continued

2011 SGO News: GI Risk Clarified for Bevacizumab

2011 SGO News: GI Risk Clarified for Bevacizumab

Ovarian cancer patients had a twofold greater risk of gastrointestinal adverse effects when bevacizumab was added to chemotherapy, but the angiogenesis inhibitor did not exacerbate other known risks for GI events, data from a large prospective trial showed.

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