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Diet May Influence Ovarian Cancer Survival

Diet May Influence Ovarian Cancer Survival

According to a new study published in the Journal of the National Cancer Institute, a good diet before diagnosis is linked with lower mortality among ovarian cancer survivors. Researchers analyzed data from 636 cases of ovarian cancer among postmenopausal women within the Women’s Health Initiative Observational Study or Clinical Trials from 1993 to 1998. The … Continued

Use of Intensive Medical Services for Ovarian Cancer Patien...

Use of Intensive Medical Services for Ovarian Cancer Patients at End of Life Increases Despite Rise in Use of Hospice

There have been widespread efforts to improve the quality of life of terminally ill patients. As more patients choose to spend their final days and weeks in hospice care rather than a hospital, the hope is the use of intensive and costly hospital services would decline. A large new study by Dana-Farber Cancer Institute researchers … Continued

Telomere Length and Mortality Following An Ovarian Cancer D...

Telomere Length and Mortality Following An Ovarian Cancer Diagnosis

Telomeres are essential for the maintenance of chromosomal integrity. Telomere shortening leads to genomic instability, which is hypothesized to play a role in cancer development and prognosis. New data published in Cancer Epidemiology, Biomarkers & Prevention, provide preliminary evidence that telomere length likely does not predict outcome after a diagnosis of ovarian cancer. This represents … Continued

Detection of Gene Mutations in Tampons of Patients With Hig...

Detection of Gene Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer

(October 14, 2014) In a pilot study published in the journal Obstetrics & Gynecology, researchers detected DNA derived from tumor cells in the vaginas of 60% of patients with ovarian cancer with intact fallopian tubes. With further development, this approach may hold promise for the early detection of this deadly disease. Click here to read … Continued

Ovarian Cancer Oncogene Found in ‘Junk DNA’

Ovarian Cancer Oncogene Found in ‘Junk DNA’

(October 6, 2014) A research team based at the University of Pennsylvania mined junk DNA sequences to identify a non-protein-coding RNA whose expression is linked to ovarian cancer.  The study, which was published in Cancer Cell, was supported in part by an OCRF research grant to Lin Zhang, MD. The researchers built a DNA copy … Continued

Partner Member Profile: Lilies of the Valley

Partner Member Profile: Lilies of the Valley

Lilies of the Valley got its start in 2004 when a new gynecologic oncologist moved to the city of Huntsville, Alabama. His wife had a friend with ovarian cancer, and she noticed that there were no support groups available for women with this disease. Current Executive Director Regina Parker recalls: “She got together with some … Continued

SGO Perspectives on Endpoints for Studies of Ovarian Cancer

SGO Perspectives on Endpoints for Studies of Ovarian Cancer

(Sept. 29, 2014) In a perspective piece for the website MedPage Today, representatives from the Society of Gynecologic Oncology discuss clinical endpoints appropriate for studies addressing the “unique characteristics” of ovarian cancer and progress toward improving outcomes for women affected by the disease. In the article, co-authors Thomas J. Herzog, MD, of the University of Cincinnati … Continued

Maintenance Pazopanib in Ovarian Cancer: No Survival Benefi...

Maintenance Pazopanib in Ovarian Cancer: No Survival Benefit, High Rate of Complications

(Sept. 25, 2014) Maintenance therapy with the oral agent pazopanib improved progression free survival (PFS) by a median of 5.6 months in patients with advanced ovarian cancer but did not impact overall survival, according to the results of a phase III randomized trial reported in the Journal of Clinical Oncology. In this clinical trial, which … Continued

OCRF Research Finds Metastasis Promoted by Mesothelial Cells

OCRF Research Finds Metastasis Promoted by Mesothelial Cells

A new study in the Journal of Clinical Investigation indicates that mesothelial cells actively promote the spread of ovarian cancer. Using a three dimensional culture model of ovarian cancer metastasis, OCRF grantee and Scientific Advisory Committee Member Ernst Lengyel, MD, PhD, and colleagues at the Unviersity of Chicago found that in the presence of cancer … Continued

Call for Ideas Now Open for the Ovarian Cancer Translationa...

Call for Ideas Now Open for the Ovarian Cancer Translational Research Dream Team Grant

A Collaboration of Stand Up To Cancer, Ovarian Cancer Research Fund, Ovarian Cancer National Alliance and National Ovarian Cancer Coalition PHILADELPHIA — The American Association for Cancer Research (AACR) is now accepting submissions of ideas for the Stand Up To Cancer (SU2C)-Ovarian Cancer Research Fund (OCRF)-Ovarian Cancer National Alliance (OCNA)-National Ovarian Cancer Coalition (NOCC) Translational … Continued

Ovarian Cancer Dream Team Call for Ideas Now Open

Ovarian Cancer Dream Team Call for Ideas Now Open

The American Association for Cancer Research is now accepting submissions of ideas for the new Stand Up To Cancer Ovarian Cancer Translational Research Dream Team Grant that will offer up to $6 million in research funding, which includes $3 million provided by the leading funder, OCRF. The Stand Up To Cancer-Ovarian Cancer Research Fund-Ovarian Cancer … Continued

New Study Shows No Association between Powder Use and Ovari...

New Study Shows No Association between Powder Use and Ovarian Cancer

(September 12, 2014) A new study published in the Journal of the National Cancer Institute this month suggests that use of perineal powder does not influence ovarian cancer risk. In the past, some studies have suggested that there is an increased risk of ovarian cancer among talc users.  In this new and large prospective study, … Continued

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