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New Report Recommends Classifying Cancer by Genetic and Mol...

New Report Recommends Classifying Cancer by Genetic and Molecular Type

(August 21, 2014) A research network in the US proposes that cancer should be classified according to genetic and molecular features rather than by the type of tissue in which the tumor arises. While more work is needed to confirm and build on the findings, the scientists say such a system would be better for … Continued

Newk's Eatery Launches Ovarian Cancer Awareness Month ...

Newk's Eatery Launches Ovarian Cancer Awareness Month Campaign to Boost Early Detection, Raise Funds for Research and Inspire Hope

Campaign at Newk’s 70 fast-casual restaurants runs through Ovarian Cancer Awareness Month JACKSON, Miss. (August 20, 2014) — The fast-casual Newk’s Eatery restaurant brand is joining forces with one of its own to launch a Newk’s Cares campaign with Ovarian Cancer Research Fund (OCRF). The campaign will raise awareness about early detection, raise funds for … Continued

Drug Combination Impacts Outcomes in Ovarian Cancer Patient...

Drug Combination Impacts Outcomes in Ovarian Cancer Patients without BRCA Mutations

BRCA mutations in ovarian cancer are a double-edged sword.  While BRCA gene mutation carriers have a significantly higher risk of developing ovarian cancer, BRCA gene mutation in tumors is associated with a significant increase in patient survival.  Scientists believe that this is because loss of BRCA gene expression leads to an increase tumor cell response … Continued

Partner Member Profile: OCERN

Partner Member Profile: OCERN

For the founders of OCERN, the Ovarian Cancer Education & Research Network, Inc., becoming a Partner Member of the Alliance was a “no brainer.” Executive Director Gina Dayton notes that the founders believed in a three-pronged approach to ovarian cancer outreach: “We wanted to advance research and continue to educate others about the symptoms—but we … Continued

Epigenetic Targeting of Ovarian Cancer Stem Cells

Epigenetic Targeting of Ovarian Cancer Stem Cells

(July 29, 2014)   OCRF-funded research published earlier this month provides the first proof of principle that epigenomic strategies efficiently target ovarian cancer stem cells, which are key for treatment resistance and the major factor in therapy failures.  OCRF grantees Kenneth Nephew, PhD and Daniela Matei, MD are first and senior author of the paper, which was … Continued

Partner Member Profile: No to O

Partner Member Profile: No to O

When her ovarian cancer recurred in 2010, Jean Ebert sought treatment in Chapel Hill, North Carolina. She soon connected with another woman who had been diagnosed around the same time—2008—with the same stage of ovarian cancer. Jean and Charlotte quickly formed a connection. “She wanted to do something and I wanted to do something,” recalls … Continued

Most High Risk Women Aren't Aware of Ovarian Cancer Risk

Most High Risk Women Aren't Aware of Ovarian Cancer Risk

(July 28, 2014) Research published last week in Behavioral Medicine suggests that most high-risk women (>75%) do not know their risk for ovarian cancer. Women with a documented deleterious mutation in BRCA1 or BRCA2 are at substantially elevated risk for ovarian cancer. To understand what percentage of women with high risk family histories know their … Continued

Help Make Cancer a Part of the Past with Summer's Hott...

Help Make Cancer a Part of the Past with Summer's Hottest Shopping Bash

QVC and Ovarian Cancer Research Fund Promote National Awareness During the “QVC Presents Super Saturday LIVE” Broadcast WEST CHESTER, Pa. (July 22, 2014) – Shop for a cure with designer bargains galore. QVC and Ovarian Cancer Research Fund (OCRF) are joining forces once again for “QVC Presents Super Saturday LIVE,” an annual “designer charity sale” … Continued

OCRF Research Sheds New Light on Ovarian Cancer Metastasis

OCRF Research Sheds New Light on Ovarian Cancer Metastasis

(July 21, 2014) According to research funded in part by OCRF, circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs. This new finding, supported in part by an OCRF Program Project Development Grant to Anil Sood, MD, … Continued

Stand Up to Cancer Returns to Primetime on Friday, Septembe...

Stand Up to Cancer Returns to Primetime on Friday, September 5 for its Fourth Star-Studded Broadcast

LIVE, ONE-HOUR FUNDRAISING EVENT TO AIR SIMULTANEOUSLY ON ABC, CBS, FOX, NBC AND 26 BROADCAST AND CABLE NETWORKS 8 PM ET & PT / 7PM CT Broadcast Coincides with Live Stand Up To Cancer Canada Event, with Canadian-Inclusive Telecast for Canadian Audience July 9, 2014 (Los Angeles / New York) – Building on three historic … Continued

OCRF Research Shows ARID1A is Tumor Suppressor Gene

OCRF Research Shows ARID1A is Tumor Suppressor Gene

(July 8, 2014) Frequent mutations in the ARID1A gene have been previously discovered in ovarian endometrioid and clear-cell cancers.  Now research supported by OCRF has provided direct evidence that it is an authentic tumor suppressor gene using a mouse model.  OCRF Ann Schreiber Mentored Investigator grantee Bin Guan, PhD is first author, and OCRF Scientific … Continued

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