OCRA is proud to announce the launch of the Rare Ovarian Cancer Collaborative Analytics (ROCCA) Platform, an international federated data network funded by OCRA to connect researchers globally and accelerate breakthroughs in rare ovarian cancer research. A collaborative approach to research for rare ovarian cancer ROCCA is launching with two foundational projects: one in mucinous … Continued
Research Breakthrough: At The Ohio State University Medical Center, researchers found that among people diagnosed with an early ovarian cancer precursor, older patients and Black patients face worse survival, underscoring the urgent need for more tailored care and treatment strategies. Serous tubal intraepithelial carcinoma (STIC) is a rare lesion in the fallopian tube that is … Continued
Research Breakthrough: Researchers at Ohio State University found that probiotic supplements may help gynecologic cancer patients reduce radiation-related gut side effects like diarrhea and cramping, while prebiotics alone showed little benefit. Researchers at the Ohio State University Medical Center performed a systematic review to look at whether probiotics (beneficial live microbes) and prebiotics (fiber that … Continued
Research Breakthrough: Researchers at the University of Texas MD Anderson Cancer Center discovered that blocking a key nutrient while also using immunotherapy could offer a promising new treatment strategy for around half of ovarian clear cell cancers, a disease with limited therapeutic options. Clear cell ovarian cancer is a rare but especially difficult form of … Continued
Research Breakthrough: Researchers at the University of Texas MD Anderson Cancer Center identified key gene changes in certain mucinous ovarian cancers with potential to guide care and predict outcomes when identified through genetic testing at diagnosis. Mucinous ovarian cancer is a rare type of ovarian cancer that behaves differently from more common forms, and doctors … Continued
Research Breakthrough: At The University of Chicago, researchers systematically tested existing therapies to find an effective drug combination that shows promise as a treatment for ovarian cancer. Scientists are looking for better ways to treat high-grade serous ovarian cancer, especially the cancer cells that survive standard chemotherapy (carboplatin) and lead to recurrence. In this study, researchers … Continued
Research Breakthrough: A team of researchers at The University of Texas Health Science Center developed a pioneering AI tool to better predict treatment response, a step toward earlier personalized treatment plans. The researchers created a new artificial intelligence tool that uses images from diagnostic laparoscopy, minimally invasive camera-made images taken inside the abdomen, to predict how patients … Continued
Research Breakthrough: Scientists at The University of Texas MD Anderson Cancer Center uncovered key differences in immune environments between primary tumors and metastases that may explain why high-grade serous ovarian carcinoma often suppresses the immune system. High-grade serous ovarian carcinoma (HGSC) tumors are often able to suppress the immune system to evade being detected and … Continued
A study published in Nature Cancer details how OCRA-funded research has dramatically expanded the impact of DNA and RNA data in the Cancer Genome Atlas and Cancer Cell Line Encyclopedia, by analyzing samples for protein expression related to cancer. The research team behind the study includes Dr. Gordon Mills, an Ovarian Cancer Research Alliance grantee … Continued
OCRA’s 2024 Mentored Investigator Grants are supporting fresh perspectives and approaches to end ovarian and related gynecologic cancers. This year’s grants are awarded to 5 exceptional young researchers who are conducting promising studies under the mentorship of leaders in the gynecologic cancer field. “OCRA’s Mentored Investigators exemplify the innovative spirit and dedication needed to make … Continued
OCRA’s 2024 Early Career Investigator Grants are awarded to 8 outstanding young researchers with a strong commitment to ending ovarian and related gynecologic cancers. These grants fund innovative projects, and support the next generation of scientists dedicated to curing ovarian cancer. “By supporting these early career investigators, we’re fostering innovative approaches and fresh perspectives into … Continued
OCRA’s Health Equity Research Grants for 2024 are dedicated to advancing equity in care of ovarian and related gynecologic cancers, addressing deep disparities in early diagnosis, access to care, and patient outcomes. “In a year of remarkable new research being undertaken by OCRA-funded scientists, our expanded focus on health equity is more critical than ever,” … Continued
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