Search Results for “brca”

Oct 15, 2015

BRCA Mutations Confer Risk, Even in Absence of Family History

...family history of the disease, 6 were found to have mutations in BRCA1 andBRCA2. Six of the 59 cases without family history were also found to have BRCA1/2 germline mutations,...

Jan 22, 2015

BRCA1/2 Mutations and 10 year Survival in Ovarian Cancer

(January 22, 2015) In a study published in Clinical Cancer Research, researchers analyzed the effect of germline mutations in BRCA1 and BRCA2 on mortality in ovarian cancer patients up to...

Apr 15, 2015

BRCA Cancer Risk Differs With Type and Location of Mutations

(April 15, 2015) Doctors have long recognized that women with mutations in two particular genes – BRCA1 and BRCA2 – have a higher risk of breast and ovarian cancer. Now...

Jul 29, 2020

Science Made Simple: BRCA Mutations

...our body fights off diseases. The BRCA gene is one such gene. (Or, two genes actually – BRCA1 and BRCA2.) The name “BRCA” stands for “BReast CAncer gene.” These genes produce a...

Oct 19, 2017

OCRFA Funded Study Discovers 3 Key Genes in Prevention and Treatment of BRCA1 and BRCA2 Tumors

(October 19, 2017) BRCA1 and BRCA2 are among the most frequently mutated genes in ovarian cancer. Studies conducted in the past two decades have shown that BRCA1 and BRCA2 play...

Jun 30, 2017

Age-Specific Risk in Women with BRCA1 and BRCA2 Mutations

...and 17 percent for BRCA2 carriers and that cancer risk varied by mutation location within the BRCA1 or BRCA2 gene. “The results indicate that family history is a strong risk...

Oct 18, 2013

New Clue in BRCA1 and BRCA2 Mutations

A new study released in Lancet Oncology showed that abnormal levels of female hormones in the bloodstream may be why women with BRCA1 or BRCA2 mutations are at a higher risk...

Aug 11, 2014

Drug Combination Impacts Outcomes in Ovarian Cancer Patients without BRCA Mutations

Ron Buckanovich, MD, PhD BRCA mutations in ovarian cancer are a double-edged sword. While BRCA gene mutation carriers have a significantly higher risk of developing ovarian cancer, BRCA gene mutation...

Feb 25, 2014

Study Shows BRCA1 Mutation Carriers Should Remove Ovaries by Age 35

...oophorectomy) by age 35. The report studied nearly 5,800 women with specific genetic mutations called BRCA1 and BRCA2. Researchers found that women with BRCA1 and BRCA2 mutations who protectively had...

Aug 22, 2019

Should You Be Tested for BRCA Mutations? New Guidelines

...JAMA website. New BRCA Mutation Test Guidelines The USPSTF published new recommendations on risk assessment, genetic counseling, and genetic testing for BRCA mutations and BRCA-related cancers. on Should You Be...

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