Science Made Simple: BRCA Mutations
…our body fights off diseases. The BRCA gene is one such gene. (Or, two genes actually – BRCA1 and BRCA2.) The name “BRCA” stands for “BReast CAncer gene.” These genes produce a…
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Drug Combination Impacts Outcomes in Ovarian Cancer Patients without BRCA Mutations
Ron Buckanovich, MD, PhD BRCA mutations in ovarian cancer are a double-edged sword. While BRCA gene mutation carriers have a significantly higher risk of developing ovarian cancer, BRCA gene mutation…
Study Shows BRCA1 Mutation Carriers Should Remove Ovaries by Age 35
…oophorectomy) by age 35. The report studied nearly 5,800 women with specific genetic mutations called BRCA1 and BRCA2. Researchers found that women with BRCA1 and BRCA2 mutations who protectively had…
OCRFA Funded Study Discovers 3 Key Genes in Prevention and Treatment of BRCA1 and BRCA2 Tumors
(October 19, 2017) BRCA1 and BRCA2 are among the most frequently mutated genes in ovarian cancer. Studies conducted in the past two decades have shown that BRCA1 and BRCA2 play…
OCRA-Funded Study Identifies Antibiotic Found to Kill Tumor Cells Containing BRCA Mutations
…laboratory cell lines and tumor models with BRCA1 or BRCA2 genetic mutations–and is effective even in tumors that have become resistant to PARP inhibitors. Dr. Alan D’Andrea BRCA1 and BRCA2…
New Guidelines on Risk, Genetic Counseling & Testing for BRCA-related Cancer
…Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-related Cancer in Women. Ovarian Cancer Research News | Risk Assessment for BRCA-related Cancer Risk, Genetic Counseling & Testing for BRCA-related Cancer…
Breastfeeding, Birth Control Pills May Reduce Ovarian Cancer Risk Among Women with BRCA Gene Mutations
…ovaries to cut their cancer risk. Find more information in Medical Xpress. Risk Reduction for BRCA BRCA, ovarian cancer, ovarian cancer BRCA, Basser Center Breastfeeding, tubal ligation – also known…
Age-Specific Risk in Women with BRCA1 and BRCA2 Mutations
…and 17 percent for BRCA2 carriers and that cancer risk varied by mutation location within the BRCA1 or BRCA2 gene. “The results indicate that family history is a strong risk…
Oral Contraceptives Associated with Lower Ovarian Cancer Risk in BRCA Mutation Carriers
…Contraceptives & Lower Risk for BRCA Carriers An international retrospective study followed BRCA1 and BRCA2 mutation carriers to track oral contraceptive use and ovarian cancer. Here’s what they learned. oral-contraceptives-associated-with-lower-ovarian-cancer-risk-in-brca-mutation-carriers…
Should You Be Tested for BRCA Mutations? New Guidelines
…JAMA website. New BRCA Mutation Test Guidelines The USPSTF published new recommendations on risk assessment, genetic counseling, and genetic testing for BRCA mutations and BRCA-related cancers. on Should You Be…
Ovarian Cancer Risk and BRCA1 Methylation
(January 31, 2018) A study published in the Annals of Internal Medicine explains that researchers now believe that the methylation of normal BRCA1 gene promotion, not solely BRCA1 mutation, is…
OCRF Research Sheds Light on Ovarian Cancer Origins in BRCA Mutation Carriers
…cancer, ovarian cancer research, cancer ovarian, ovarian cancer news, ovarian cancer research news, BRCA ovarian cancer Ovarian Cancer Origins in BRCA Mutation Carriers Ovarian Cancer Origins in BRCA Mutation Carriers…