Search Results for “brca” - Page 12 - Ovarian Cancer Research Alliance

Mar 25, 2025

Press Release: Nearly Half of Women With Ovarian Cancer Are Not Receiving Critical Genetic Testing

...particularly in identifying BRCA mutations and other genetic markers that guide treatment with precision therapies such as PARP inhibitors. Key findings of the OCRA analysis show that only 52% of...

Nov 30, 2012

Supreme Court to Hear Gene Patent Case

The Supreme Court of the United States will hear arguments in a case seeking to invalidate the patents on the BRCA1 and BRCA2 mutations. The patent-holder, Myriad Laboratories, owns patents...

Dec 15, 2021

Ovarian Cancer Research Discoveries Made by OCRA Grantees in 2021

...models with BRCA1 or BRCA2 genetic mutations, and is effective even in tumors that have become resistant to PARP inhibitors. Found that a combination of CDK9 inhibition and PP2A activation...

Aug 11, 2025

Why I Give: Continuing the Rivkin Center Legacy with Ovarian Cancer Research Alliance

...tested negative for BRCA1 and BRCA2 mutations —inherited genetic mutations that are known to elevate risk—but Kim knows there is more to discover. That’s part of the research we need:...

Feb 3, 2015

OCRF Research Identifies Six New Susceptibility Loci for Ovarian Cancer

...million genetic variants with epithelial ovarian cancer risk and found six additional susceptibility regions, bringing the total to 18. The variants identified have a less dramatic impact than BRCA1 or...

Jan 30, 2024

Ovarian Cancer Research Alliance Awards Two Prizes Recognizing Exceptional Researchers

...to advance innovative treatment approaches for ovarian cancers involving mutations in the BRCA1 and BRCA2 genes. Dr. Verma’s independent lab integrates several cutting-edge genomics and molecular biology tools to study...

Jan 10, 2022

OCRA Awards Nearly $6.5 Million in Ovarian Cancer Research Grants

...DC, “Targeting Chromobox 2 to overcome macrophage-induced immune suppression” Sammy Ferri-Borgogno, PhD, University of Texas M.D. Anderson Cancer Center, “BRCA-deficient ovarian cancer and IFITM3: a new “power couple” Livnat Jerby,...

Aug 23, 2018

Women with Medicare Found to Have Low Genetic Testing Rates

...2009 and diagnosed with breast cancer, ovarian cancer, or both. Within this population of 718 women, 92 of them were eligible for BRCA1 and BRCA2 testing but only eight of...

Sep 30, 2022

Searching for Two Kinds of Cures | Meet a Scientist

...PARP inhibitors, and even how genetic predispositions, such as BRCA1 and BRCA2 mutations, can change the trajectory of treatment. “Our goal to these two approaches,” Ie-Ming said, “is to convert...

Jun 22, 2015

ASCO 2015 Update

...now have treatments (PARP inhibitors, such as Lynparza) to target BRCA1 and BRCA2 mutations, scientists are not yet sure how to target other mutations present in ovarian cancer tumors. With...

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