Search Results for “brca” - Page 14 - Ovarian Cancer Research Alliance

Multimodal Study Uses Machine Learning to Improve Risk-Stratification of HGSOC

...in the TGCA-OV set. To gain insights around treatment resistance, particular attention was paid to homologous recombination-deficient (HRD) disease status, presence of BRCA1 or BRCA2 mutations, and associated response to...

Screening High-Risk Women Catches More Early Stage Ovarian Cancers

...primary recommendation for women of high risk, specifically after having children, before the age of 40 for BRCA1 carriers, and before 45 years of age for BRCA2 carriers. “Up until...

Study Reveals New Mechanism of Action for PARP Inhibitors

...in their ability to kill cancer cells. PARP inhibitors are a class of drugs that have shown promising results against ovarian cancer in women with BRCA1 and BRCA2 gene mutations....

Highlights: 2022 Annual Meeting of the Society of Gynecologic Oncology (SGO)

...cancers respond to particular treatments or better tolerate treatment at a lower starting dose (predictive biomarkers). Biomarkers can be mutation carrier status (BRCA1 or 2+), molecular characteristics of tumors (HRD,...

Partner Member Profile: Hope for Heather

...in honor of Rebecca Hafner, who lost her life to ovarian cancer. They partner with breast cancer organizations to hold combined events, raising awareness about the BRCA1 and BRCA2 inherited...

For Some, Statin Use Can Decrease the Risk of Ovarian Cancer

...seen in women who were BRCA1 or BRCA2 positive or women who were premenopausal. 11 on For Some, Statin Use Can Decrease the Risk of Ovarian Cancer The best outcomes...

Nicola Meagher, PhD

...in BRCA genes and homologous recombination deficiency) is a critical access step in increasing treatment options. The tests can also identify whether relatives have an increased risk of ovarian cancer,...

Hao Nie, PhD

...improve efficacy and/or overcome resistance to PARP inhibitors in EOCs with homologous recombination deficiency such as those caused by BRCA mutations. This grant was made possible in part by a...

How One Ovarian Cancer Survivor Turned Her Diagnosis Into a Mission to Save Lives | Heroes Highlights

...diagnosed with primary peritoneal cancer in 2009, which came nearly a decade after she underwent a full hysterectomy following breast cancer and the discovery of a BRCA1 genetic mutation, Jane...

OCRA Funded Research Delves Deeper into How PARPi Work

...including OCRA grantee Ursula Matulonis, MD, treated BRCA-1 deficient tumors with olaparib, a PARPi, and found that it began both a natural and medically induced antitumor process that was STING...

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Search Results for: "brca"

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Multimodal Study Uses Machine Learning to Improve Risk-Stratification of HGSOC

Screening High-Risk Women Catches More Early Stage Ovarian Cancers

Study Reveals New Mechanism of Action for PARP Inhibitors

Highlights: 2022 Annual Meeting of the Society of Gynecologic Oncology (SGO)

Partner Member Profile: Hope for Heather

For Some, Statin Use Can Decrease the Risk of Ovarian Cancer

Nicola Meagher, PhD

Hao Nie, PhD

How One Ovarian Cancer Survivor Turned Her Diagnosis Into a Mission to Save Lives | Heroes Highlights

OCRA Funded Research Delves Deeper into How PARPi Work

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