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New Study on BRCA Mutation in Women with Ovarian Cancer

New Study on BRCA Mutation in Women with Ovarian Cancer

A new study of 1,001 women with ovarian cancer found that 14% of them carried a BRCA1 or BRCA2 mutation. However, 44% of those women did not have a family history of breast or ovarian cancer. The BRCA mutations can not only help evaluate risk of developing ovarian cancer, but may direct treatment and can … Continued

Cancer Survivors Need Long Term Care

Cancer Survivors Need Long Term Care

A new article explores the long term effects of cancer care, and the unique needs of survivors. With 18 million cancer survivors expected to be alive in the United States by 2022, this follow up care is important. It may require more education of a primary care provider and/or coordination between the oncologist and primary … Continued

PARP Inhibitor Olaparib Increases Progression Free Survival

PARP Inhibitor Olaparib Increases Progression Free Survival

05/29/2012 In an abstract that will be presented at the American Society of Clinical Oncology annual meeting in Chicago this weekend, researchers report that in patients with platinum-sensitive recurrent serous ovarian cancer, olaparib plus paclitaxel plus carboplatin, followed by maintenance treatment with olaparib, resulted in a significant improvement in progression-free survival compared with paclitaxel plus … Continued

Obesity Does Not Increase Risk for Ovarian Cancer Recurrence

Obesity Does Not Increase Risk for Ovarian Cancer Recurrence

05/29/2012 Research that will be presented at the 2012 American Society of Clinical Oncology meeting June 1-5th suggests that obesity did not affect recurrence, time to recurrence, or progression-free survival in women with epithelial ovarian cancer following surgery and chemotherapy. Previous research examining the relationship between obesity and ovarian cancer has yielded mixed results. Click … Continued

Removing Fallopian Tubes Reduces Risk of Ovarian Cancer

Removing Fallopian Tubes Reduces Risk of Ovarian Cancer

Based on data showing that removing a woman’s fallopian tubes removes her risk of developing ovarian cancer, doctors are now urging women who are having their tubes tied to have them removed, instead. There is an increasing body of evidence suggesting that ovarian cancer may start in the fallopian tubes. Surgery to remove the fallopian … Continued

DNA Repair Genes May be a Predictor of Ovarian Cancer Survival

DNA Repair Genes May be a Predictor of Ovarian Cancer Survival

04/30/2012   Research published this month in the Journal of the National Cancer Institute suggests that DNA repair genes may be a predictor of ovarian cancer survival. Researchers at Dana-Farber Cancer Institute in Boston used gene expression data from The Cancer Genome Atlas database to develop a molecular “score” by looking at genes involved in … Continued

Increased BMI and Height Tied to Ovarian Cancer Risk

Increased BMI and Height Tied to Ovarian Cancer Risk

04/16/2012 Research reported in the journal PLoS Medicine finds that a woman’s Body Mass Index (BMI) and height are both tied to her risk for ovarian cancer.  Regardless of a woman’s height and size, her risk of developing ovarian cancer remains very small. Researchers from the United Kingdom included data from more than 25,000 women … Continued

Draft USPSTF Statement Recommends Against Ovarian Cancer Sc...

Draft USPSTF Statement Recommends Against Ovarian Cancer Screening

04/11/2012   In a draft statement released April 11, 2012, the U.S. Preventive Services Task Force (USPSTF) again stated that screening average-risk women for ovarian cancer does more harm than good. The USPSTF, an independent volunteer panel of non-government experts in prevention and evidence-based medicine, is composed of primary care providers (such as internists, pediatricians, family physicians, gynecologists/obstetricians, … Continued

Updates from the Society of Gynecologic Oncology Meeting

Updates from the Society of Gynecologic Oncology Meeting

04/03/2012 Members of OCRF’s senior staff and Scientific Advisory Committee recently attended the Society of Gynecologic Oncology (SGO) Annual Meeting on Women’s Cancer in Austin, TX. Now in its 43rd year, the Annual Meeting on Women’s Cancer continues to be the premier educational activity for women’s cancer care professionals. Data Confirm PARP Inhibitor Slows Ovarian … Continued

OCRF Invited to Participate in Important New National Resea...

OCRF Invited to Participate in Important New National Research Initiative

03/06/2012   The U.S. Preventive Services Task Force (USPSTF), an independent volunteer panel of non-government experts in prevention and evidence-based medicine, is composed of primary care providers (such as internists, pediatricians, family physicians, gynecologists/obstetricians, and nurses). This prestigious group conducts rigorous scientific reviews of a broad range of clinical preventive health care services (such as screening, counseling, … Continued

OCRF Research Defines Association Between Ovarian Cancer an...

OCRF Research Defines Association Between Ovarian Cancer and Endometriosis

02/22/2012   Research by a team of scientists funded by OCRF has shown that there is an association between invasive ovarian cancer and endometriosis.  The research was reported on February 22nd in Lancet Oncology. The Ovarian Cancer Association Consortium, a collaborative created with the support of OCRF and led by grantee Dr. Andrew Berchuck, conducted an analysis … Continued

OCRF Research Explains High Platelets and Reduced Survival ...

OCRF Research Explains High Platelets and Reduced Survival in Ovarian Cancer Patients

02/17/2012 An international team of researchers led by OCRF grantee Anil Sood, MD has found that elevated platelet levels in ovarian cancer patients fuel tumor growth and reduce survival. These findings reveal a new factor in cancer progression and a possible new approach for treatment. The study, which was reported in the New England Journal of Medicine, was … Continued

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