In a review article published online in Oncogene on August 12, OCRF-funded researchers provide a comprehensive review of pre-clinical models used in ovarian cancer research. The authors, including OCRF grantees Ernst Lengyel, Daniela Matei, Ken Nephew, and Joanna Burdette, explore current experimental models and reflect on the strengths and weaknesses for each method. In addition, extensive information on the origins of many ovarian cancer cell lines, stem cell markers, and ovarian cancer models are included in the appendix.
The authors hope that the review will be a useful resource for all ovarian cancer researchers, new and experienced alike.
Click here to read the abstract.