Partner Member Profile: Hope for Heather
…in honor of Rebecca Hafner, who lost her life to ovarian cancer. They partner with breast cancer organizations to hold combined events, raising awareness about the BRCA1 and BRCA2 inherited…
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For Some, Statin Use Can Decrease the Risk of Ovarian Cancer
…seen in women who were BRCA1 or BRCA2 positive or women who were premenopausal. 11 on For Some, Statin Use Can Decrease the Risk of Ovarian Cancer The best outcomes…
OCRA Funded Research Delves Deeper into How PARPi Work
…including OCRA grantee Ursula Matulonis, MD, treated BRCA-1 deficient tumors with olaparib, a PARPi, and found that it began both a natural and medically induced antitumor process that was STING…
Veliparib Trial Fails to Improve Outcomes in Ovarian Cancer
…with cyclophosphamide alone, according to a phase II study evaluating patients with high-grade serous ovarian cancer, peritoneal, fallopian tube, and BRCA-mutant ovarian cancers. The research was reported in Clinical Cancer…
OCRA Awards Millions in New Ovarian Cancer Research Grants
…for Immunology, “Studying the role of BRCA1 in regulating heterochromatin structure and function in ovarian cancer” Bojana Stefanovska, PhD, University of Minnesota – Twin Cities, “APOBEC3B and DNA Repair as…
Niraparib Approved for Maintenance Treatment of Ovarian Cancer
…to be approved by the FDA that does not require BRCA mutation or other biomarker testing. TESARO anticipates launching niraparib in the United States in late April. READ MORE… 11…
A New Report from USPSTF
…in improving benefits and reducing harmful outcomes.” The report also calls for genetic counseling for women with increased risk of BRCA mutations. The USPSTF is an independent panel of health…
Some Fallopian Tube Lesions Represent Ovarian Cancer Metastases, Not Precursor Lesions
…population levels. In studying the origin of HGSC, it remains important to separate cases driven by germline mutations in BRCA1/2 or other ovarian cancer susceptibility genes from sporadic carcinomas. Eckert…
At Your Own Pace, In Your Own Space: How to Be a Hero in a Pandemic
…in her abdomen that Amy learned she had ovarian cancer. (She also had genetic testing and learned that she was positive for the BRCA gene mutation.) A project is born…
Impact of Genetic Counseling on Testing and Surgical Prevention in High Risk Women
…and prophylactic surgery. Guidelines recommend genetic counseling and testing for women who have a pedigree suggestive of an inherited susceptibility for ovarian cancer (for example, BRCA1 and 2 genes). The…
Ask the SAC | Why Is the Number of Ovarian Cancer Diagnoses Decreasing?
…risk-reducing surgery in patients with BRCA or other high-risk mutations, and increase in opportunistic salpingectomy.” “Likely many reasons — more use of oral contraceptive pills (OCPs), less hormone replacement, better awareness,…
Our Response to Angelina
…that she has a mutation in the BRCA gene, which increases her risk of breast and ovarian cancers. The Alliance received many calls and requests to comment from media outlets….