A False Alarm, and a Wake-Up Call to Fight Ovarian Cancer
…that can be treated with precision medicine, much in the same way that doctors now know how to treat patients with BRCA mutations using PARP inhibitors. Naming the motivation Rugang…
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FDA Seeking Comments on Olaparib by June 11
…for women with platinum-sensitive relapsed ovarian cancer (including fallopian tube or primary peritoneal) with germline BRCA mutation as detected by an FDA-approved test, who are in response (complete response or…
Combination Niraparib plus Pembrolizumab Shows Promise
…patients with ovarian carcinoma who have limited treatment options regardless of platinum status, biomarker status, or prior treatment with bevacizumab. Responses in patients without tumor BRCA mutations or non-HRD cancers…
Blazing New Trails | Meet a Scientist
…She was a fellow and helped to treat Gilda Radner when she had ovarian cancer. Beth was struck by Gilda’s strong family history of cancer, and when the BRCA genes…
Racial Disparities in Ovarian Cancer are Real
…common in Black women BRCA mutations are not common in Black women Black women are not willing to undergo treatment Black people have less sensitive nerve endings To repeat, the…
FDA Approves Rucaparib as Maintenance Treatment for Platinum Sensitive Recurrent Ovarian Cancer
…statistically significant difference between the drug and the placebo, regardless of BRCA status. “Both the efficacy and safety results from the ARIEL3 study reinforce the important role of Rubraca (rucaparib)…
Denmark Study Shows Assisted Reproduction Does Not Increase Risk of Ovarian Cancer
…for her infertility. The biggest risk factors for ovarian cancer are still age and genetic factors, such as BRCA mutations. Dr. Pinborg, a gynecologist in the Fertility Department at Copenhagen…
Statins Present New Directions for Ovarian Cancer Research
…carried the BRCA1/2 fault, of whom 3,887 had ovarian cancer, were also studied. Mendelian randomization, which involves analyzing the genetic data from thousands of people, was used to examine the…
Writing for Her Life | OCRA Heroes
…monies raised. But she needed a name for that fund. “I started thinking about where my genetics came from,” said Jane who learned she was a BRCA gene mutation carrier,…
New Research Shows Cervical Cells May Hold Key to Predicting Ovarian Cancer Risk
…risk of these cancers (e.g., people with a BRCA alteration or family history).” Study: Cervical Cells and Ovarian Cancer Risk Prediction A new study suggests that cell samples that are routinely collected…
OCRA-Funded Study Discovers Potential Target for Overcoming Treatment Resistance
…this new study, working with a range of ovarian cancer cells, with and without BRCA mutations, researchers found that PGCCs appeared more often in all tumors that were resistant to…
ASCO News: Two New Drugs Show Promise for Recurrent Ovarian Cancer
…serous or was related to a BRCA gene mutation, or change, received either olaparib by itself or olaparib plus cediranib. Researchers found that 80% of the women who received the…