Search Results for “brca” - Page 14 - Ovarian Cancer Research Alliance

Nov 14, 2012

Study Reveals New Mechanism of Action for PARP Inhibitors

...in their ability to kill cancer cells. PARP inhibitors are a class of drugs that have shown promising results against ovarian cancer in women with BRCA1 and BRCA2 gene mutations....

Dec 20, 2013

Partner Member Profile: Hope for Heather

...in honor of Rebecca Hafner, who lost her life to ovarian cancer. They partner with breast cancer organizations to hold combined events, raising awareness about the BRCA1 and BRCA2 inherited...

Nov 13, 2018

For Some, Statin Use Can Decrease the Risk of Ovarian Cancer

...seen in women who were BRCA1 or BRCA2 positive or women who were premenopausal. 11 on For Some, Statin Use Can Decrease the Risk of Ovarian Cancer The best outcomes...

Nicola Meagher, PhD

...in BRCA genes and homologous recombination deficiency) is a critical access step in increasing treatment options. The tests can also identify whether relatives have an increased risk of ovarian cancer,...

Hao Nie, PhD

...improve efficacy and/or overcome resistance to PARP inhibitors in EOCs with homologous recombination deficiency such as those caused by BRCA mutations. This grant was made possible in part by generous...

Jul 9, 2026

OCRA Rivkin Family SummeRun Returns July 12 to Honor a Lasting Legacy and Fund Ovarian Cancer Research

...that she carried a BRCA1 mutation, Garza underwent surgery just four months after receiving what appeared to be normal test results, only to discover she had stage 3 ovarian cancer....

Dec 21, 2018

OCRA Funded Research Delves Deeper into How PARPi Work

...including OCRA grantee Ursula Matulonis, MD, treated BRCA-1 deficient tumors with olaparib, a PARPi, and found that it began both a natural and medically induced antitumor process that was STING...

Jan 26, 2015

Veliparib Trial Fails to Improve Outcomes in Ovarian Cancer

...with cyclophosphamide alone, according to a phase II study evaluating patients with high-grade serous ovarian cancer, peritoneal, fallopian tube, and BRCA-mutant ovarian cancers. The research was reported in Clinical Cancer...

Jan 27, 2021

OCRA Awards Millions in New Ovarian Cancer Research Grants

...for Immunology, “Studying the role of BRCA1 in regulating heterochromatin structure and function in ovarian cancer” Bojana Stefanovska, PhD, University of Minnesota – Twin Cities, “APOBEC3B and DNA Repair as...

Mar 28, 2017

Niraparib Approved for Maintenance Treatment of Ovarian Cancer

...to be approved by the FDA that does not require BRCA mutation or other biomarker testing. TESARO anticipates launching niraparib in the United States in late April. READ MORE… 11...

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