…associated with an increased risk for potentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2). Women with a positive screen should receive genetic counseling and, if indicated after counseling, BRCA…

A new study released in Lancet Oncology showed that abnormal levels of female hormones in the bloodstream may be why women with BRCA1 or BRCA2 mutations are at a higher risk…

…the BRCA2 gene, the research showed. “BRCA1 carriers had a more favorable survival than noncarriers, which improved slightly after additional adjustment for stage, grade, histology, and age at diagnosis. BRCA2…

…family history of the disease, 6 were found to have mutations in BRCA1 andBRCA2. Six of the 59 cases without family history were also found to have BRCA1/2 germline mutations,…

…should be offered BRCA1/2 mutation testing. Researchers from the Peter MacCallum Cancer Centre in East Melbourne, Australia, screened 1,001 women with ovarian cancer to investigate the impact of germ-line BRCA1…

…mutation status and extent of residual disease post-surgery. Results showed that by 10-years of follow-up, 43% of non-carriers, 57% of BRCA1 mutation carriers and 69% of BRCA2 mutation carriers had…

(January 22, 2015) In a study published in Clinical Cancer Research, researchers analyzed the effect of germline mutations in BRCA1 and BRCA2 on mortality in ovarian cancer patients up to…

…et al. v. Myriad Genetics, the court considered the validity of patents held by the Utah-based company Myriad Genetics for the BRCA1 and BRCA2 genes, which when mutated are associated…

…looked at both copies of the BRCA genes, one copy given by each parent. Until recently, it had been assumed that mutated BRCA gene left the non-mutated gene defunct, which…

…investigate long-term survival (10 years post diagnosis) in BRCA mutation carriers. Their results show that “for women with invasive ovarian cancer, the short-term survival advantage of carrying a BRCA1 or…

(April 15, 2015) Doctors have long recognized that women with mutations in two particular genes – BRCA1 and BRCA2 – have a higher risk of breast and ovarian cancer. Now…