Search Results for “brca” - Page 7 - Ovarian Cancer Research Alliance

Oct 12, 2012

Q&A with Sarah Adams, M.D., 2011 Liz Tilberis Awardee

...research. SA: Women with ovarian cancers that result from an inherited mutation in the BRCA gene show excellent response to a drug called a PARP inhibitor. The drug specifically kills...

Dec 17, 2015

Team Twedt: Taking on Ovarian Cancer, One Ironman at a Time

...genetic makeup – a BRCA gene mutation. Dawn and Jamie A Tough Decision Her sister and mother had it, and both had been diagnosed with cancer – first her mother...

Aug 21, 2015

Multi-gene Testing for Ovarian Cancer Risk is Clinically Useful

...(which looks for mutations in many genes), identifies more people with cancer risk related gene mutations than screening for BRCA1 and 2 alone. Importantly, identifying these additional gene mutations provides...

Jul 15, 2021

The Overview: July 2021

...tumor cells in laboratory cell lines and tumor models with BRCA1 or BRCA2 genetic mutations. Read on to discover how it has been found to be effective even in tumors that have...

Sep 11, 2015

Teaming Up Against Ovarian Cancer

...cancers. Specifically, we are targeting the cell’s repair mechanism, which mends breaks in the DNA and corrects mistakes. In cancer cells, defects in the BRCA1 or BRCA2 genes cause one...

Sep 10, 2015

Teaming Up Against Ovarian Cancer

...in the DNA and corrects mistakes. In cancer cells, defects in the BRCA1 or BRCA2 genes cause one of the repair mechanisms, or pathways, to lose function. In the absence...

Dec 20, 2018

FDA Approves Olaparib for Frontline Maintenance Treatment in Ovarian Cancer

...to 70% in women with BRCA 1 or 2 positive, advanced stage epithelial ovarian, fallopian tube, and primary peritoneal cancers. Those included in the study received cytoreductive surgery and had...

Jul 23, 2015

OCRF Research Shows PARP/Immune Therapy Combo Shows Promise

...a mouse model of BRCA1-deficient ovarian cancer. Combining a PARP-inhibitor with immune therapy resulted in tumor rejection and long-term survival in a mouse model of BRCA1-deficient ovarian cancer. 19 19...

Dec 20, 2017

OCRFA Research Shows Novel Combination Therapy Effective in Ovarian Cancer

...cancer patients without BRCA mutations. The research was funded in part by an OCRFA grant to Rugang, Zhang, PhD. PARP inhibitors have already been approved to treat BRCA-mutant ovarian cancers,...

Jul 28, 2023

Can a Pap Smear Detect Ovarian Cancer? A Comprehensive Look

...linked to genetic mutations, such as BRCA1 and BRCA2, highlighting the importance of genetic testing, especially for those with a family history of ovarian, breast, colorectal, prostate, and uterine cancers....

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Search Results for: "brca"

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Q&A with Sarah Adams, M.D., 2011 Liz Tilberis Awardee

Team Twedt: Taking on Ovarian Cancer, One Ironman at a Time

Multi-gene Testing for Ovarian Cancer Risk is Clinically Useful

The Overview: July 2021

Teaming Up Against Ovarian Cancer

Teaming Up Against Ovarian Cancer

FDA Approves Olaparib for Frontline Maintenance Treatment in Ovarian Cancer

OCRF Research Shows PARP/Immune Therapy Combo Shows Promise

OCRFA Research Shows Novel Combination Therapy Effective in Ovarian Cancer

Can a Pap Smear Detect Ovarian Cancer? A Comprehensive Look

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