Search Results for “brca” - Page 17 - Ovarian Cancer Research Alliance

May 22, 2014

FDA Seeking Comments on Olaparib by June 11

...for women with platinum-sensitive relapsed ovarian cancer (including fallopian tube or primary peritoneal) with germline BRCA mutation as detected by an FDA-approved test, who are in response (complete response or...

Jun 18, 2019

Combination Niraparib plus Pembrolizumab Shows Promise

...patients with ovarian carcinoma who have limited treatment options regardless of platinum status, biomarker status, or prior treatment with bevacizumab. Responses in patients without tumor BRCA mutations or non-HRD cancers...

Mar 16, 2020

Blazing New Trails | Meet a Scientist

...She was a fellow and helped to treat Gilda Radner when she had ovarian cancer. Beth was struck by Gilda’s strong family history of cancer, and when the BRCA genes...

Feb 1, 2021

Racial Disparities in Ovarian Cancer are Real

...common in Black women BRCA mutations are not common in Black women Black women are not willing to undergo treatment Black people have less sensitive nerve endings To repeat, the...

Apr 10, 2018

FDA Approves Rucaparib as Maintenance Treatment for Platinum Sensitive Recurrent Ovarian Cancer

...statistically significant difference between the drug and the placebo, regardless of BRCA status. “Both the efficacy and safety results from the ARIEL3 study reinforce the important role of Rubraca (rucaparib)...

Jul 12, 2018

Denmark Study Shows Assisted Reproduction Does Not Increase Risk of Ovarian Cancer

...for her infertility. The biggest risk factors for ovarian cancer are still age and genetic factors, such as BRCA mutations. Dr. Pinborg, a gynecologist in the Fertility Department at Copenhagen...

Mar 17, 2020

Statins Present New Directions for Ovarian Cancer Research

...carried the BRCA1/2 fault, of whom 3,887 had ovarian cancer, were also studied. Mendelian randomization, which involves analyzing the genetic data from thousands of people, was used to examine the...

Apr 15, 2020

Writing for Her Life | OCRA Heroes

...the monies raised. But she needed a name for that fund. “I started thinking about where my genetics came from,” said Jane who learned she was a BRCA gene mutation...

Feb 9, 2022

New Research Shows Cervical Cells May Hold Key to Predicting Ovarian Cancer Risk

...risk of these cancers (e.g., people with a BRCA alteration or family history).” Study: Cervical Cells and Ovarian Cancer Risk Prediction A new study suggests that cell samples that are routinely collected...

Sep 22, 2023

OCRA-Funded Study Discovers Potential Target for Overcoming Treatment Resistance

...this new study, working with a range of ovarian cancer cells, with and without BRCA mutations, researchers found that PGCCs appeared more often in all tumors that were resistant to...

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