Search Results for “brca” - Page 17 - Ovarian Cancer Research Alliance

Apr 10, 2018

FDA Approves Rucaparib as Maintenance Treatment for Platinum Sensitive Recurrent Ovarian Cancer

...statistically significant difference between the drug and the placebo, regardless of BRCA status. “Both the efficacy and safety results from the ARIEL3 study reinforce the important role of Rubraca (rucaparib)...

Jul 12, 2018

Denmark Study Shows Assisted Reproduction Does Not Increase Risk of Ovarian Cancer

...for her infertility. The biggest risk factors for ovarian cancer are still age and genetic factors, such as BRCA mutations. Dr. Pinborg, a gynecologist in the Fertility Department at Copenhagen...

Mar 17, 2020

Statins Present New Directions for Ovarian Cancer Research

...carried the BRCA1/2 fault, of whom 3,887 had ovarian cancer, were also studied. Mendelian randomization, which involves analyzing the genetic data from thousands of people, was used to examine the...

Apr 15, 2020

Writing for Her Life | OCRA Heroes

...the monies raised. But she needed a name for that fund. “I started thinking about where my genetics came from,” said Jane who learned she was a BRCA gene mutation...

Feb 9, 2022

New Research Shows Cervical Cells May Hold Key to Predicting Ovarian Cancer Risk

...risk of these cancers (e.g., people with a BRCA alteration or family history).” Study: Cervical Cells and Ovarian Cancer Risk Prediction A new study suggests that cell samples that are routinely collected...

Sep 22, 2023

OCRA-Funded Study Discovers Potential Target for Overcoming Treatment Resistance

...this new study, working with a range of ovarian cancer cells, with and without BRCA mutations, researchers found that PGCCs appeared more often in all tumors that were resistant to...

Jun 4, 2014

ASCO News: Two New Drugs Show Promise for Recurrent Ovarian Cancer

...serous or was related to a BRCA gene mutation, or change, received either olaparib by itself or olaparib plus cediranib. Researchers found that 80% of the women who received the...

Jun 29, 2020

Finding Sparks, Fueling Motivation | Meet a Scientist

...for the laymen and women: our bodies have genes whose jobs are to keep our cells from becoming cancerous tumors. Sometimes these genes become mutated, such as the BRCA mutation,...

Feb 14, 2018

US Preventive Services Task Force: Ovarian Cancer Screening Not Effective for Low-Risk Women

...of the disease, or with BRCA1/2 genetic mutations. The complete recommendation was published in JAMA, with several accompanying editorials in related publications by experts in the field who offer their...

Jul 27, 2021

High-Grade Serous Carcinoma

...some patients, especially those with BRCA mutations. In 2020, PARP inhibitors received FDA approval as first-line therapy for a subset of patients with advanced ovarian cancers, and has been shown to...

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