Search Results for “brca” - Page 4 - Ovarian Cancer Research Alliance

Apr 1, 2014

Discoverer of BRCA genes said “being ignored” helped her do her research

Last week marked the 20th year anniversary of the discovery of the BRCA1 gene by Mary-Claire King, Ph.D., an American geneticist. Dr. King, who was interviewed last week by NPR,...

May 4, 2018

Hormone Replacement Therapy After Oophorectomy Is Not Shown to Increase Risk of Breast Cancer in BRCA1 Mutation Carriers

(May 4, 2018) JAMA Oncology recently published a study that looked at the risk of breast cancer in BRCA1 carriers who underwent a prophylactic bilateral salpingo-oophorectomy, a surgery that removes...

Dec 19, 2016

Rucaparib FDA Approved for Advanced Ovarian Cancer with BRCA Mutations

...women with advanced ovarian cancer who have been treated with two or more chemotherapies and whose tumors have a specific gene mutation (deleterious BRCA) as identified by an FDA-approved companion...

May 15, 2013

Alliance Responds to Angelina Jolie's BRCA1 Announcement

Actress Angelina Jolie recently announced that she carries a mutation in the BRCA1 gene, which makes her more likely to develop breast and ovarian cancer. In the wake of that...

Current Grantees

Explore OCRA’s grant recipients pioneering ovarian cancer research across the US. Learn about their innovative projects shaping the future of cancer treatment.

Jan 11, 2022

Hereditary Breast and Ovarian Cancer Syndrome (HBOC)

...BRCA positive.” What they mean is that a genetic test has shown that they have harmful changes in either the BRCA1 or BRCA2 gene that increase their risk of ovarian or...

Nov 30, 2022

Germline vs Somatic Testing; Genomic vs Genetic Testing — What it Means and Why it Matters

...you have this mutation? BRCA 1 and 2 genes are known as tumor suppressor genes, because they control proteins that work with DNA to repair the body. Everyone has BRCA...

Prevention & Risk

Learn about ovarian cancer risk factors and prevention strategies. Understand your risk, genetic testing options, and proactive steps to lower your risk today.

Jul 18, 2023

Jill Martin Shares Important Breast and Ovarian Cancer Prevention Message

...her mother’s negative BRCA gene mutations test result. However, prompted by her doctors, she took an at-home saliva test, and discovered that she carries a BRCA 2 mutation inherited from...

Feb 7, 2017

OCRFA Research Finds New Gene Mutation Spurs Cancer Growth

...understand to have a role similar to those of BRCA1 and BRCA2. BRCA1 and BRCA2 are well known genes that, when working, help with DNA damage repair, which protects the...

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