Search Results for “brca” - Page 16 - Ovarian Cancer Research Alliance

May 12, 2021

Can You Get Ovarian Cancer At Any Age?

...ovarian, uterine, prostate, or colorectal cancer before age 50 Are of Ashkenazi or Eastern European Jewish ancestry, as BRCA mutations are more common among this group Have endometriosis Experience early...

Dec 9, 2013

Then & Now: 20 Years and Still Going Strong

...found out that I have the BRCA1 gene mutation that put me at a greater risk of breast and ovarian cancer. While no one I knew of in my family...

Nov 3, 2015

Research Round Up: AACR

...of drugs could be expand the use of PARP inhibitors beyond women with BRCA mutations. Suffice to say, it’s an exciting time with lots of potential. Immunotherapy Researchers also spent...

Mar 14, 2013

IP Chemo Shows Survival Benefit

Two studies recently released show a survival benefit for intraperitoneal IP chemotherapy Women with the BRCA1 mutation given IP chemotherapy survived three years longer than those given IV chemotherapy. Read...

Aug 25, 2023

Going Online to Garner Support and Awareness

...research study included genetic testing that resulted in Sam being notified that she carries a BRCA2 gene variant, which is associated with an increased risk of developing ovarian and other...

Oct 6, 2014

Ovarian Cancer Oncogene Found in ‘Junk DNA’

...long noncoding RNAs, or lncRNAs across 12 cancer types, including ovarian and breast cancers that include the two major BRCA-related cancers. They found that the number of copies of lncRNA...

Oct 30, 2017

New Research Indicates that High Grade Serous Ovarian Carcinomas Originate in the Fallopian Tubes

...of whom also carried other high-risk mutations, such as BRCA or PTEN. “These data provide much-needed insights into the etiology of ovarian cancer and have important implications for prevention, early...

Mar 1, 2021

A False Alarm, and a Wake-Up Call to Fight Ovarian Cancer

...that can be treated with precision medicine, much in the same way that doctors now know how to treat patients with BRCA mutations using PARP inhibitors. Naming the motivation Rugang...

May 22, 2014

FDA Seeking Comments on Olaparib by June 11

...for women with platinum-sensitive relapsed ovarian cancer (including fallopian tube or primary peritoneal) with germline BRCA mutation as detected by an FDA-approved test, who are in response (complete response or...

Jun 18, 2019

Combination Niraparib plus Pembrolizumab Shows Promise

...patients with ovarian carcinoma who have limited treatment options regardless of platinum status, biomarker status, or prior treatment with bevacizumab. Responses in patients without tumor BRCA mutations or non-HRD cancers...

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