Search Results for “brca” - Page 6 - Ovarian Cancer Research Alliance

Apr 1, 2014

Updates from the 2014 Society for Gynecologic Oncology Annual Meeting

...Recent research suggests that between 11 and 18% of ovarian cancers arise because of genetic mutation in one of 13 genes, including the well-recognized BRCA1 and BRCA2, but also the...

Dec 20, 2022

2022 Breakthroughs in Ovarian Cancer Research and Treatment

...cancer. The most common type of mutations linked to ovarian cancer are ones that occur in the BRCA genes associated with DNA repair: BRCA1 (BReast CAncer gene 1) and BRCA2...

Apr 3, 2018

Genetic Counseling and Testing by Oncologists Feasible for Ovarian Cancer Patients

...BRCA mutations was worthwhile, as was the ENGAGE testing guidelines. The study concluded that oncologist led BRCA mutation testing via these guidelines was well received and could offer a faster,...

Oct 11, 2016

Niraparib Significantly Improves Outcome of Ovarian Cancer Patients

...and without germline BRCA mutations. In a randomized, double-blind, phase III trial of over 550 women both with and without germline BRCA mutations, researchers found that patients receiving niraparib once...

Jan 8, 2016

OCRF Research Finds Inherited Mutations in 18% with Ovarian Cancer

...BRCA2. Learn more. Of the 1,915 patients surveyed, eighteen percent carried a gene mutation known to be associated with ovarian cancer, such as BRCA1 and BRCA2. Learn more. 19 19...

Priyanka Verma, PhD

2023 Early Career Investigator Grant Washington University in St. Louis Project Summary Mutations in genes involved in the BReast CAncer (BRCA)-dependent DNA repair pathway represent approximately 50% of high-grade serous...

Maria Victoria Botuyan, PhD

...53BP1 – regulate HR DNA repair. BRCA1-BARD1 and RAD18 activate HR DNA repair while 53BP1 inactivates HR DNA repair. A correct balance of BRCA1-BARD1, RAD18 and 53BP1 is needed for...

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