Search Results for “brca” - Page 9 - Ovarian Cancer Research Alliance

Jun 17, 2014

Report from the 2014 American Society of Clinical Oncology Annual Meeting

...olaparib. BRCA positive patients had only a slight increase in PFS (19.4 vs. 16.5 months), which is to be expected since PARP inhibitors are known to be highly effective in BRCA positive women. Yet,...

Jan 2, 2013

Partner Member Profile: Bright Pink

Lindsay Avner founded Bright Pink in 2007, shortly after she learned that she carried a mutation in the BRCA gene. Just 22 years old when she was tested, Lindsay realized...

Feb 7, 2023

OCRA Awards $7 Million in Research Grants for 2023

...Cancer Center, “Synthetic Lethality of the Protexin and BRCA Complexes in Ovarian Cancer” Brooke Howitt, MD, Stanford University, “Identifying the Cell of Origin for High Grade Serous Carcinoma” Xiaowen Hu,...

Sep 11, 2012

USPSTF Recommends Against Routine Screening For Ovarian Cancer

...at higher risk for developing ovarian cancer. Risk factors include family history of ovarian cancer, mutations in genes known to increase risk (BRCA1 and BRCA2), diagnosis of pre-menopausal breast cancer...

Oct 12, 2012

Q&A with Melinda Yates, Ph.D.

...research findings into advances that can improve health outcomes in women at high-risk for ovarian cancer due to inherited mutations in the BRCA1 and BRCA2 genes. Dr. Yates has received...

Apr 24, 2023

Study Finds Genetic Testing Underutilized Among Ovarian Cancer Patients

...While the numbers of those tested increased over time, and especially accelerated after the approval of PARP inhibitors for BRCA1 and BRCA2 mutated chemotherapy-refractory ovarian cancer in December 2014, the...

Jun 21, 2016

June 2016 ASCO Highlights

...intravenous chemotherapy and stating that BRCA1/2 patients could benefit from the use of IP. All agreed that there are unresolved issues regarding the use of IP chemotherapy and much work...

Mar 29, 2013

New Genetic Markers for Ovarian Cancer Discovered

...were identified for breast (n = 1) and ovarian (n = 2) cancers in BRCA1 mutation carriers and for breast cancer (n = 1) in BRCA2 mutation carriers. An epigenetic...

Jun 20, 2016

Highlights from the June 2016 American Society of Clinical Oncology (ASCO) Annual Meeting

...114, and 172) resulted in longer PFS using intraperitoneal compared to intravenous chemotherapy and stating that BRCA1/2 patients could benefit from the use of IP. All agreed that there are...

May 4, 2020

Niraparib Receives FDA Approval as First-Line Maintenance Therapy for Advanced Ovarian Cancer

...regardless of BRCA mutation status. Niraparib was first approved by the FDA for treatment of recurrent ovarian cancer in 2017. This most recent approval means ovarian cancer patients do not...

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